Johannes von Lintig

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Case Western Reserve University School of Medicine

United States

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Professor Johannes von Lintig is a faculty member at Case Western Reserve University School of Medicine in the United States. His research focuses on the absorption, metabolism, and transport of carotenoids and retinoids, with a particular emphasis on the role of dietary factors and genetics in vitamin A homeostasis. Recent articles by Professor von Lintig explore various aspects of oxidative stress responses, mitochondrial carotenoid transport, and the implications of maternal genetics on obesity susceptibility in offspring.

Recent Grants

Grant: Close

STRA6 and Ocular Vitamin A Homeostasis

Open Date: 2018-08-01

Close Date: 2023-07-31

Grant: Close

Carotenoids in Vision

Open Date: 2009-11-01

Close Date: 2020-03-31

Grant: Close

Molecular Components Affecting Ocular Vitamin A homeostasis

Open Date: 2009-08-01

Close Date: 2012-07-01

Grant: Close

Functional characterization of Carotenoid-Dioxygenases and their role in embryonic development

Open Date: 2001-01-01

Close Date: 2007-12-31

Articles (18)

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2025

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2023

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2022

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2022

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2022

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2022

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2022

Collaborators (1)

Yoshikazu Imanishi

Lois Letzter Associate Professor of Ophthalmology

Indiana University School of Medicine

UNITED STATES

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Johannes von Lintig

Research Interests

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Recent Grants

Articles (18)

Aster-B Modulates Oxidative Stress Responses and Carotenoid Distribution in ARPE-19 Cells

Distinct pathways for the absorption and metabolism of β-carotene and zeaxanthin in the mouse intestine

Maternal genetics and diet modulate vitamin A homeostasis of the offspring and affect the susceptibility to obesity in adulthood in mice

The Absorption, Storage, and Transport of Ocular Carotenoids and Retinoids

Unraveling the mystery of ocular retinoid turnover: Insights from albino mice and the role of STRA6

Genetic deletion of Bco2 and Isx establishes a golden mouse model for carotenoid research

Vitamin A deficiency compromises the barrier function of the retinal pigment epithelium

ASTER-B regulates mitochondrial carotenoid transport and homeostasis

β-Cryptoxanthin Attenuates Cigarette-Smoke-Induced Lung Lesions in the Absence of Carotenoid Cleavage Enzymes (BCO1/BCO2) in Mice

ASTER-B regulates mitochondrial carotenoid transport and homeostasis

Bioavailability and provitamin A activity of neurosporaxanthin in mice

Genetic deletion of Bco2 and Isx establishes a golden mouse model for carotenoid research

Aster la vista: Unraveling the biochemical basis of carotenoid homeostasis in the human retina

Genetic tuning of β-carotene oxygenase-1 activity rescues cone photoreceptor function in STRA6-deficient mice

Diabetes Aggravates Photoreceptor Pathologies in a Mouse Model for Ocular Vitamin A Deficiency

Genetic dissection in mice reveals a dynamic crosstalk between the delivery pathways of vitamin A

Aster proteins mediate carotenoid transport in mammalian cells

The vitamin A transporter STRA6 adjusts the stoichiometry of chromophore and opsins in visual pigment synthesis and recycling

Collaborators (1)

Yoshikazu Imanishi

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