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John C. Byrd

UPMC Hillman Cancer Center

United States

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Professors in United States

Articles (21)

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Collaborators (23)

John Sanchez

The University of Texas MD Anderson Cancer Center

UNITED STATES

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Shelley Orwick

Ohio State University

UNITED STATES

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Parvathi Ranganathan

Associate Professor with Tenure

Ohio State University

UNITED STATES

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Elie Traer

Oregon Health & Science University

UNITED STATES

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Mitch Phelps

Ohio State University

UNITED STATES

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Tara Lin

University of Kansas Medical Center

UNITED STATES

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Samir Poudel

Middle Tennessee State University

UNITED STATES

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Christopher Jensen

University of North Carolina

UNITED STATES

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Zulfa Omer

Assistant Professor, Hematology and Medical Oncology division

UNITED STATES

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Thomas Kipps

Distinguished Professor

University of California, San Diego

UNITED STATES

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Deepa Sampath

The University of Texas MD Anderson Cancer Center

UNITED STATES

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Eric Eisenmann

Ohio State University

UNITED STATES

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Sharyn D. Baker

Ohio State University

UNITED STATES

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Alexander Marr

The University of Kansas Health System

UNITED STATES

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Kritagya Upadhyay

Assistant Professor

Middle Tennessee State University

UNITED STATES

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Talha Munir

UNITED KINGDOM

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Wendy Stock

Professor of Medicine

University of Chicago

UNITED STATES

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Manali Kamdar

University of Colorado

UNITED STATES

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Ola Elgamal

University of Cincinnati

UNITED STATES

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Deborah Stephens

Assistant Professor

Huntsman Cancer Institute

UNITED STATES

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Anna Candoni

Docenti di ruolo di IIa fascia

University of Modena and Reggio Emilia

ITALY

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Joshua Zeidner

Associate Professor of Medicine

University of North Carolina, Lineberger Comprehensive Cancer Center

UNITED STATES

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Marc Hoffmann

Assistant Professor

University of Kansas Cancer Center

UNITED STATES

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John C. Byrd

Research Interests

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Articles (21)

PKCβ Inhibitor MS-553 Displays Preclinical Efficacy in Both Treatment-Naïve and BTK Inhibitor-Resistant Chronic Lymphocytic Leukemia

DHODH inhibition alters T cell metabolism limiting acute graft-versus-host disease while retaining graft-versus-leukemia response.

Feasibility of Bruton’s Tyrosine Kinase Inhibitor Discontinuation in Chronic Lymphocytic Leukemia: The Patient Perspective

A Phase 1b/2 Study of TP-0903 and Decitabine Targeting Mutant TP53 and/or Complex Karyotype in Patients with Untreated Acute Myeloid Leukemia ≥Age 60 Years

CD37 in acute myeloid leukemia: a novel surface target for drug delivery

A Blockchain and IoT-Enabled Framework for Ethical and Secure Coffee Supply Chains

Azacitidine, Venetoclax, and Revumenib for Newly Diagnosed NPM1 -Mutated or KMT2A -Rearranged AML

Acalabrutinib-obinutuzumab improves survival vs chemoimmunotherapy in treatment-naive CLL in the 6-year follow-up of ELEVATE-TN

Addition of Ianalumab (VAY736) to Ibrutinib in Patients with Chronic Lymphocytic Leukemia on Ibrutinib Therapy: Results from a Phase Ib Study

Bexobrutideg (NX-5948), a novel Bruton's tyrosine kinase (BTK) degrader, demonstrates rapid and durable clinical responses in Relapsed/Refractory chronic lymphocytic leukemia (CLL): New and updated findings from an ongoing Phase la/b trial

Comprehensive comparison of enzymatic and bisulfite DNA methylation analysis in clinically relevant samples

Cytarabine Pharmacogenomics and Outcomes Among Children and Young Adults With Acute Myeloid Leukemia

Efficacy and safety in a 4-year follow-up of the ELEVATE-TN study comparing acalabrutinib with or without obinutuzumab versus obinutuzumab plus chlorambucil in treatment-naive chronic lymphocytic leukemia (Dec, 10.1038/s41375-024-02487-1, 2024)

Exploiting RAS pathway addiction as a therapeutic vulnerability in myeloid sarcoma

How well does acalabrutinib work and how safe is it to treat patients with chronic lymphocytic leukemia/small lymphocytic lymphoma who have had previous treatments? a plain language summary of 2 key studies

Long-term survival can be achieved in a significant fraction of older patients with core-binding factor acute myeloid leukemia treated with intensive chemotherapy

Loss of the Y chromosome defines a biologically distinct subtype of Acute Myeloid Leukemia (AML), associated with decreased inflammatory response patterns, and favorable outcomes in young male patients (pts)

MOLECULAR PHARMACOLOGY AND DRUG RESISTANCE: LYMPHOID NEOPLASMS Targeting BTKi-resistant CLL using the dual irreversible/reversible 4th generation BTK inhibitor rocbrutinib

MYD88 mutations in clonal hematopoiesis promote inflammation and hematopoietic stem cell expansion

LP-118 is a novel B-cell lymphoma 2 / extra-large inhibitor that demonstrates efficacy in models of venetoclax-resistant chronic lymphocytic leukemia

First-in-Human Study of the Reversible BTK Inhibitor Nemtabrutinib in Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia and B-Cell Non–Hodgkin Lymphoma

Collaborators (23)

John Sanchez

Shelley Orwick

Parvathi Ranganathan

Elie Traer

Mitch Phelps

Tara Lin

Samir Poudel

Christopher Jensen

Zulfa Omer

Thomas Kipps

Deepa Sampath

Eric Eisenmann

Sharyn D. Baker

Alexander Marr

Kritagya Upadhyay

Talha Munir

Wendy Stock

Manali Kamdar

Ola Elgamal

Deborah Stephens

Anna Candoni

Joshua Zeidner

Marc Hoffmann

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