John Chatham

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The University of Alabama

United States

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Recent Grants

Grant: Close

STIM1 mediated calcium entry: A new paradigm of metabolic regulation of cardiomyo

Open Date: 2012-04-15

Close Date: 2014-02-28

Grant: Close

O-GlcNAcylation and Hippocampal Synaptic Plasticity

Open Date: 2011-06-01

Close Date: 2016-05-31

Grant: Close

Protein O-GlcNAcylation and the regulation of cardiac function

Open Date: 2010-07-01

Close Date: 2014-05-31

Grant: Close

O-linked glycosylation and synaptic function in hippocampus

Open Date: 2009-05-15

Close Date: 2012-04-30

Grant: Close

Mechanisms of glucosamine ischemic cardioprotection

Open Date: 2006-04-01

Close Date: 2013-03-31

Articles (18)

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UNITED STATES

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Adam Wende

Associate Professor

The University of Alabama

UNITED STATES

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Paul Gregorevic

University of Melbourne

AUSTRALIA

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Laura Parry

University of Adelaide

AUSTRALIA

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Joshua Anderson

University of Alabama, Tuscaloosa

UNITED STATES

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Michelle Johnson

The University of Alabama

UNITED STATES

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John Chatham

Research Interests

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Recent Grants

Articles (18)

Impact of O-GlcNAcylation Elevation on Mitophagy and Glia in the Dentate Gyrus

Brain Transcriptome Changes Associated With an Acute Increase of Protein O-GlcNAcylation and Implications for Neurodegenerative Disease

Severe attenuation of circadian clock output in the heart following sustained augmentation of cardiomyocyte protein O-GlcNAcylation

Protein glycosylation in cardiovascular health and disease

Forskolin reverses the O-GlcNAcylation dependent decrease in GABA<inf>A</inf>R current amplitude at hippocampal synapses possibly at a neurosteroid site on GABA<inf>A</inf>Rs

The role of protein O-GlcNAcylation in diabetic cardiomyopathy

Cardiomyocyte ZKSCAN3 regulates remodeling following pressure‐overload

Best practices in assessing cardiac protein O-GlcNAcylation by immunoblot

Enzyme-based assay for quantification of UDP-GlcNAc in cells and tissues

Relationships between gene expression and behavior in mice in response to systemic modulation of the O-GlcNAcylation pathway

The interplay between sex, time of day, fasting status, and their impact on cardiac mitochondrial structure, function, and dynamics

Sustained Increases in Cardiomyocyte Protein O-Linked β-N-Acetylglucosamine Levels Lead to Cardiac Hypertrophy and Reduced Mitochondrial Function Without Systolic Contractile Impairment

Cardiomyocyte stromal interaction molecule 1 is a key regulator of Ca 2+ ‐dependent kinase and phosphatase activity in the mouse heart

Acute inhibition of OGA sex-dependently alters the networks associated with bioenergetics, autophagy, and neurodegeneration

Fine-tuning the cardiac O-GlcNAcylation regulatory enzymes governs the functional and structural phenotype of the diabetic heart.

STIM and Orai Mediated Regulation of Calcium Signaling in Age-Related Diseases

The Identification of a Novel Calcium-Dependent Link Between NAD<sup>+</sup> and Glucose Deprivation-Induced Increases in Protein O-GlcNAcylation and ER Stress.

Branched chain amino acids selectively promote cardiac growth at the end of the awake period.

Collaborators (10)

Helen Collins

Sobuj Mia

Rakesh Patel

Min Xie

Jianhua Zhang

Adam Wende

Paul Gregorevic

Laura Parry

Joshua Anderson

Michelle Johnson

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