John D. Hulleman

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University of Texas Southwestern Medical Center

United States

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Recent Grants

Grant: Close

Core Grant for Vision Research

Open Date: 2019-09-30

Close Date: 2024-06-30

Grant: Close

Prevention of macular pathophysiology associated with F3 misfolding

Open Date: 2018-02-01

Close Date: 2023-01-31

Grant: Close

A broadly applicable, regulatable strategy to control signaling in the retina.

Open Date: 2017-09-30

Close Date: 2020-06-30

Articles (10)

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2023

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2022

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2022

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2022

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2022

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2021

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2020

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2020

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2020

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2020

Collaborators (7)

Emmanuelle Souzeau

Flinders University

AUSTRALIA

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Maddineni Prabhavathi

Assistant Professor

University of Missouri

UNITED STATES

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Seher Yuksel

University of Texas Southwestern Medical Center

UNITED STATES

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Kathryn P Burdon

University of Tasmania

AUSTRALIA

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Terri Young

Professor

University of Wisconsin-Madison

UNITED STATES

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Emma M Wade

University of Otago

NEW ZEALAND

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Gracen Collier

University of Texas Southwestern Medical Center

UNITED STATES

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John D. Hulleman

Research Interests

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Recent Grants

Articles (10)

Forward genetic screening using fundus spot scale identifies an essential role for Lipe in murine retinal homeostasis

Specifications of the ACMG/AMP variant curation guidelines for myocilin

Development of a New DHFR-Based Destabilizing Domain with Enhanced Basal Turnover and Applicability in Mammalian Systems

A loss‐of‐function cysteine mutant in fibulin‐3 (EFEMP1) forms aberrant extracellular disulfide‐linked homodimers and alters extracellular matrix composition

A Simple Secretion Assay for Assessing New and Existing Myocilin Variants

Clinically-identified C-terminal mutations in fibulin-3 are prone to misfolding and destabilization.

Fibulin-3 knockout mice demonstrate corneal dysfunction but maintain normal retinal integrity

Two C-terminal sequence variations determine differential neurotoxicity between human and mouse α-synuclein.

Trinucleotide Repeat-Targeting dCas9 as a Therapeutic Strategy for Fuchs' Endothelial Corneal Dystrophy.

Protocol for In Vivo Evaluation and Use of Destabilizing Domains in the Eye, Liver, and Beyond.

Collaborators (7)

Emmanuelle Souzeau

Maddineni Prabhavathi

Seher Yuksel

Kathryn P Burdon

Terri Young

Emma M Wade

Gracen Collier

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