John D. Lambris

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United States

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Recent Grants

Grant: Close

Complement inhibition as sepsis therapy

Open Date: 2011-08-02

Close Date: 2015-04-30

Grant: Close

Complement in AMD: Mechanisms and Therapeutic Intervention

Open Date: 2011-02-01

Close Date: 2015-01-31

Grant: Close

Thermodynamic and structural studies on the formation of the C3 convertase

Open Date: 2007-07-01

Close Date: 2013-06-30

Grant: Close

Complement in inflammatory diseases: mechanisms &therapeutic modulation

Open Date: 2006-04-01

Close Date: 2019-05-31

Grant: Close

The role of complement in ovarian cancer

Open Date: 2005-08-01

Close Date: 2011-05-31

Articles (14)

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2025

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2021

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2020

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2020

Collaborators (8)

George Hajishengallis

Professor

University of Pennsylvania

UNITED STATES

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Hala Chaaban

University of Oklahoma Health Sciences Center

UNITED STATES

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Christina Lamers

Junior Professor

Leipzig University

GERMANY

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Benjamin Storm

Associate Professor

Nord University

NORWAY

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Georgios Kotsakis

Associate Professor

University of Texas Health Science Center at San Antonio

UNITED STATES

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Narcis Popescu

Research Associate Professor

Oklahoma Medical Research Foundation

UNITED STATES

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Daniel Ricklin

Associate Professor

University of Basel

SWITZERLAND

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Jenny Ting

Wm. Rand Kenan Professor

University of North Carolina at Chapel Hill

UNITED STATES

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John D. Lambris

Research Interests

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Contact this professor

Recent Grants

Articles (14)

‘Complement-ing’ tissue inflammation via granzyme K?

Monocyte uptake of polymeric peptidoglycan is bimodal and governed by complement C3 and C4 opsonins

Clinical C3 Inhibition With AMY-101 Reveals Novel Insights Into IL-8-Driven Inflammation in COVID-19

Pegcetacoplan (SyfovreΤΜ): targeting complement C3 in geographic atrophy

Complement‐targeted therapeutics: An emerging field enabled by academic drug discovery

The Complement-Targeted Inhibitor Mini-FH Protects against Experimental Periodontitis via Both C3-Dependent and C3-Independent Mechanisms

Compstatins: the dawn of clinical C3-targeted complement inhibition.

Considering innate immune responses in SARS-CoV-2 infection and COVID-19

C3-targeted therapy in periodontal disease: moving closer to the clinic.

Air Bubbles Activate Complement and Trigger Hemostasis and C3-Dependent Cytokine Release Ex Vivo in Human Whole Blood.

CD14 inhibition improves survival and attenuates thrombo‐inflammation and cardiopulmonary dysfunction in a baboon model of Escherichia coli sepsis

Phase IIa clinical trial of complement C3 inhibitor AMY-101 in adults with periodontal inflammation

Author Correction: Complement as a target in COVID-19?

Complement as a target in COVID-19?

Collaborators (8)

George Hajishengallis

Hala Chaaban

Christina Lamers

Benjamin Storm

Georgios Kotsakis

Narcis Popescu

Daniel Ricklin

Jenny Ting

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