John Ligon

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Assistant Professor

University of Florida

United States

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John Ligon is an Assistant Professor at the University of Florida, specializing in pediatric cancer immunotherapy and gene therapy. His recent research focuses on the implications of race and ethnicity in the treatment outcomes of pediatric acute lymphoblastic leukemia, as well as the effects of gene-edited CAR T cells. Dr. Ligon is also involved in multidisciplinary approaches for fertility preservation in young cancer patients and the real-world challenges of accessing CAR T-cell therapy.

Recent Grants

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Laboratory Research Fellowship Training in Pediatric Oncology/Hematology

Open Date: 2016-07-01

Close Date: 2020-06-01

Articles (14)

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SSM Health Cardinal Glennon Children’s Hospital

UNITED STATES

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John Ligon

Research Interests

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Recent Grants

Articles (14)

Gene-edited CAR T cells: going the distance in B-ALL

Role of race and ethnicity in survival among children/young adults with relapsed ALL: a Children's Oncology Group report

Access to CARe: A Narrative of Real‐World Medical Decision‐Making to Access Chimeric Antigen Receptor (CAR) T‐Cell Therapy in Children, Adolescents, and Young Adults

Pediatric Cancer Immunotherapy and Potential for Impact on Fertility: A Need for Evidence-Based Guidance

INSPIRED Symposium Part 4B: Chimeric Antigen Receptor T Cell Correlative Studies—Established Findings and Future Priorities

Emerging frontiers in immuno- and gene therapy for cancer

A multidisciplinary pediatric oncofertility team improves fertility preservation and counseling across 7 years

A Phase II Trial of Guadecitabine in Children and Adults with SDH-Deficient GIST, Pheochromocytoma, Paraganglioma, and HLRCC-Associated Renal Cell Carcinoma

CD19/22 CAR T cells in children and young adults with B-ALL: phase 1 results and development of a novel bicistronic CAR.

The impact of race, ethnicity, and obesity on CAR T-cell therapy outcomes

Fertility and CAR T-cells: Current practice and future directions

Consequences of hemophagocytic lymphohistiocytosis‐like cytokine release syndrome toxicities and concurrent bacteremia

Pathways of immune exclusion in metastatic osteosarcoma are associated with inferior patient outcomes

The Immunosuppressive Niche of Soft-Tissue Sarcomas is Sustained by Tumor-Associated Macrophages and Characterized by Intratumoral Tertiary Lymphoid Structures

Collaborators (5)

Hao-Wei Wang

Christian Capitini

Patrick Hanley

Grégoire Altan-Bonnet

Margaret Cupit-Link

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