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John Mariani

Assistant Professor

University of Rochester

United States

Research Interests

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Articles (8)

Year:

2026

Year:

2026

Year:

2025

Year:

2025

Year:

2024

Year:

2023

Year:

2023

Year:

2023

Collaborators (6)

Hans Jacob Teglbjærg Stephensen

Københavns Universitet

DENMARK

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Steven Goldman

Professor

University of Copenhagen

DENMARK

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Steven Schanz

University of Rochester

UNITED STATES

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Masaki Takasugi

Associate Professor

Osaka University Graduate School of Medicine

JAPAN

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Jon Sporring

Professor

Københavns Universitet

DENMARK

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Stephan Emmrich

Junior Research Group Leader

University Hospital Frankfurt

GERMANY

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John Mariani

Research Interests

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Articles (8)

Charting the transition from in vitro gliogenesis to the in vivo maturation of human glial progenitor cells transplanted into the hypomyelinated mouse brain

Efficient targeting of human glial progenitor cells in vivo with engineered AAV vectors and glymphatic delivery.

Human glial progenitors transplanted into Huntington disease mice normalize neuronal gene expression, dendritic structure, and behavior

In vivo selection and glymphatic delivery of AAV5 capsids engineered to target human glial progenitor cells.

Repression of developmental transcription factor networks triggers aging-associated gene expression in human glial progenitor cells

Young glial progenitor cells competitively replace aged and diseased human glia in the adult chimeric mouse brain

Glial progenitor cells of the adult human white and grey matter are contextually distinct

CD44 correlates with longevity and enhances basal ATF6 activity and ER stress resistance

Collaborators (6)

Hans Jacob Teglbjærg Stephensen

Steven Goldman

Steven Schanz

Masaki Takasugi

Jon Sporring

Stephan Emmrich

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