John Streicher

Assistant Professor

University of Arizona

United States

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John Streicher is an Assistant Professor at the University of Arizona, USA. His research focuses on pain management and neurodegenerative diseases, particularly the mechanisms of opioid analgesia, cannabinoid signaling, and the role of heat shock protein 90 in neural pathways. Recent publications include studies on opioid receptor signaling, the development of delta opioid receptor antagonists, and the effects of cannabis terpenes in pain models.

Articles (15)

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2025

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2025

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2025

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2025

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2024

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2023

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2023

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2022

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2022

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2022

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2022

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2021

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2021

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2021

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2020

Collaborators (8)

Abigail Schwarz

University of Alabama, Tuscaloosa

UNITED STATES

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Anne Murphy

Professor

University of Georgia

UNITED STATES

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Corinne Augelli-Szafran

Professor

University of Alabama, Tuscaloosa

UNITED STATES

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Tally M. Largent-Milnes

UNITED STATES

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Marilisa Pia Dimmito

University of Chieti-Pescara

ITALY

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Larry Young

Professor

Emory University

UNITED STATES

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Susruta Majumdar

Associate Professor

Washington University

UNITED STATES

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Michael Morgan

Professor

Washington State University - Vancouver

UNITED STATES

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John Streicher

Research Interests

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About

Articles (15)

Hsp90 inhibition in mouse spinal cord enhances Src kinase signaling in microglia to increase opioid antinociception

Development of Delta Opioid Receptor Antagonists Which Prevent Alzheimer’s Disease-Like Pathology in the 5X-Familial Alzheimer’s Disease [5XFAD] Mouse Model

Terpene blends from Cannabis sativa are cannabimimetic and antinociceptive in a mouse chronic neuropathic pain model via activation of adenosine A2a receptors

Select terpenes from Cannabis sativa are antinociceptive in mouse models of post-operative pain and fibromyalgia via adenosine A2a receptors

Select Minor Cannabinoids from Cannabis sativa Are Cannabimimetic and Antinociceptive in a Mouse Model of Chronic Neuropathic Pain

HSP90 inhibition in the mouse spinal cord enhances opioid signaling by suppressing an AMPK-mediated negative feedback loop

Strategies towards safer opioid analgesics—A review of old and upcoming targets

Age-Induced Changes in µ-Opioid Receptor Signaling in the Midbrain Periaqueductal Gray of Male and Female Rats

Inhibition of HSP90 Preserves Blood–Brain Barrier Integrity after Cortical Spreading Depression

Extracellular Alterations in pH and K+ Modify the Murine Brain Endothelial Cell Total and Phospho-Proteome

Correction: Tanguturi et al. Discovery of Novel Delta Opioid Receptor (DOR) Inverse Agonist and Irreversible (Non-Competitive) Antagonists. <i>Molecules</i> 2021, <i>26</i>, 6693

Discovery of Novel Delta Opioid Receptor (DOR) Inverse Agonist and Irreversible (Non-Competitive) Antagonists

Cannabis sativa terpenes are cannabimimetic and selectively enhance cannabinoid activity

Use of home cage wheel running to assess the behavioural effects of administering a mu/delta opioid receptor heterodimer antagonist for spontaneous morphine withdrawal in the rat

Developing Cyclic Opioid Analogues: Fluorescently Labeled Bioconjugates of Biphalin

Collaborators (8)

Abigail Schwarz

Anne Murphy

Corinne Augelli-Szafran

Tally M. Largent-Milnes

Marilisa Pia Dimmito

Larry Young

Susruta Majumdar

Michael Morgan

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