John Tyson

Professor

Virginia Polytechnic Institute and State University

United States

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John Tyson is a Professor at Virginia Polytechnic Institute and State University in the United States. His research focuses on cell cycle dynamics, including stochastic modeling of cell behavior, bistability in mitotic regulation, and the evolution of molecular regulatory networks. Recent articles highlight his work on cellular decision-making processes and mechanisms governing stem cell domains.

Articles (15)

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2024

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2023

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2023

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2022

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2022

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2022

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2022

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UNITED STATES

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Jana Wolf

Prof.

Freie Universität Berlin

GERMANY

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Bela Novak

University of Oxford

UNITED KINGDOM

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Janani Ravi

Assistant Professor

University of Colorado Anschutz Medical Campus

UNITED STATES

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John Tyson

Research Interests

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Articles (15)

Julian Hirniak, an early proponent of periodic chemical reactions

The bistable mitotic switch in fission yeast

The oscillation of mitotic kinase governs cell cycle latches in mammalian cells

Stochastic Boolean model of normal and aberrant cell cycles in budding yeast

Evolutionary Stability of Small Molecular Regulatory Networks That Exhibit Near-Perfect Adaptation

Feedback in the β-catenin destruction complex imparts bistability and cellular memory

A dynamical model of growth and maturation in Drosophila

Nucleation of stem cell domains in a bistable activator–inhibitor model of the shoot apical meristem

Time-keeping and decision-making in living cells: Part II

Time-keeping and decision-making in the cell cycle

Time-keeping and decision-making in living cells: Part I

Mathematical analysis of robustness of oscillations in models of the mammalian circadian clock

From the Belousov–Zhabotinsky reaction to biochemical clocks, traveling waves and cell cycle regulation

Computational modeling of unphosphorylated CtrA:Cori binding in the Caulobacter cell cycle

Mechanisms of signalling-memory governing progression through the eukaryotic cell cycle

Collaborators (8)

Niklas Manz

Jing Chen

Alexander Shingleton

Konstantin Doubrovinski

Andrew L Paek

Jana Wolf

Bela Novak

Janani Ravi

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