John Woolford

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Carnegie Mellon University

United States

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Recent Grants

Grant: Close

"Yeast Ribosome Biogenesis"

Open Date: 2018-03-01

Close Date: 2026-02-01

Grant: Close

III-CTX-Small: Adaptive Integration of Structured and Unstructured Data from Many Sources in a Biological Domain

Open Date: 2008-09-01

Close Date: 2012-08-31

Grant: Close

Roles of Ribosomal Proteins in Eukaryotic Ribosome Assembly In Vivo

Open Date: 2008-08-01

Close Date: 2011-07-31

Grant: Close

GENETICS OF YEAST PREMRNA SPLICING

Open Date: 1990-09-29

Close Date: 2001-06-30

Grant: Close

REGULATION OF YEAST RIBOSOMAL PROTEIN GENE EXPRESSION

Open Date: 1985-02-01

Close Date: 1990-01-31

Articles (7)

Year:

2023

Year:

2023

Year:

2022

Year:

2022

Year:

2021

Year:

2020

Year:

2020

Collaborators (1)

JESUS DE LA CRUZ

Full Professor

SPAIN

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John Woolford

Research Interests

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Recent Grants

Articles (7)

Yeast ribosome biogenesis factors Puf6 and Nog2 and ribosomal proteins uL2 and eL43 act in concert to facilitate the release of nascent large ribosomal subunits from the nucleolus.

Unraveling the influences of sequence and position on yeast uORF activity using massively parallel reporter systems and machine learning.

Additional principles that govern the release of pre-ribosomes from the nucleolus into the nucleoplasm in yeast.

Ribosomal protein eL39 is important for maturation of the nascent polypeptide exit tunnel and proper protein folding during translation.

The nucleolus as a polarized coaxial cable in which the rDNA axis is surrounded by dynamic subunit-specific phases.

Structural insights into assembly of the ribosomal nascent polypeptide exit tunnel

Coupling of 5S RNP rotation with maturation of functional centers during large ribosomal subunit assembly

Collaborators (1)

JESUS DE LA CRUZ

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