Jonathan Ma

Assistant Professor

United States

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Dr. Jonathan Ma is an Assistant Professor at the Children's Hospital of Richmond at VCU, USA. His research primarily focuses on the mechanisms of neutrophil elastase in pulmonary diseases, particularly its role in phagocytic failure and airway mucus barriers. Recent publications highlight his work on interactions of neutrophil elastase with SARS-CoV-2 and the development of novel therapeutic approaches targeting airway mucus in cystic fibrosis.

Articles (11)

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2025

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2023

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2023

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2023

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2022

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2021

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2021

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2021

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2021

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2020

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2020

Collaborators (3)

Qingguo Xu

Assistant Professor

Virginia Commonwealth University

UNITED STATES

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Guihong Chai

Research Assistant Professor

Virginia Commonwealth University

UNITED STATES

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Reinout A. Bem

NETHERLANDS

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Jonathan Ma

Research Interests

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Articles (11)

Neutrophil elastase activates macrophage calpain as a mechanism for phagocytic failure

Neutrophil elastase decreases SARS-CoV-2 spike protein binding to human bronchial epithelia by clipping ACE-2 ectodomain from the epithelial surface

Airway mucus in pulmonary diseases: Muco-adhesive and muco-penetrating particles to overcome the airway mucus barriers.

The effect of oral guaifenesin on pediatric chronic rhinitis: A pilot study.

Infection and Inflammation MUC Up the Cystic Fibrosis Airway.

Neutrophil Elastase Triggers the Release of Macrophage Extracellular Traps: Relevance to CF.

Neutrophil Elastase-Regulated Macrophage Sheddome/ Secretome and Phagocytic Failure.

Polysulfated Hyaluronan GlycoMira-1111 Inhibits Elastase and Improves Rheology in Cystic Fibrosis Sputum.

Neutrophil Extracellular Traps Increase Airway Mucus Viscoelasticity and Slow Mucus Particle Transit

Dry powder aerosol containing muco-inert particles for excipient enhanced growth pulmonary drug delivery.

Rational use of mucoactive medications to treat pediatric airway disease.

Collaborators (3)

Qingguo Xu

Guihong Chai

Reinout A. Bem

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