Jonathan Mochel

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University of Georgia

United States

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Recent Grants

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A Large-Scale Microfluidics Platform for Accelerating Toxicology Testing using Animal- Based Organoids

Open Date: 2019-08-01

Close Date: 2020-03-01

Grant: Close

Intesto-Guard™ Efficacy in Canine Intestinal Organoids and Live Clinical Trials for the Treatment of Chronic Enteropathies

Open Date: 2019-08-01

Close Date:

Grant: Close

Improving In Vitro Prediction of Oral Drug Permeability and Metabolism Using a novel 3D canine organoid model

Open Date: 2019-07-01

Close Date: 2020-06-01

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Preclinical Assessment of an Oral p97 Inhibitor, CB-5339, in Tumor-Bearing Dogs

Open Date: 2019-04-01

Close Date: 2019-09-01

Grant: Close

Use of Canine Enteroids/Colonoids to Explore Differences in Intestinal Absorption/Metabolism/Transporter Characteristics in Dogs as a Function of Intestinal Region, Breed, Genotype and Disease

Open Date: 2018-10-01

Close Date: 2023-09-01

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Collaborators (10)

Dipak Kumar Sahoo

College of Veterinary Medicine

UNITED STATES

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Teresa C. DeFrancesco

UNITED STATES

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David Meyerholz

Professor

The University of Iowa Roy J and Lucille A Carver College of Medicine

UNITED STATES

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Pierre‐Yves Mulon

UNITED STATES

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Lara Barron

Head of Cardiology

UNITED KINGDOM

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David Díaz-Regañón Fernández

Universidad Complutense de Madrid

SPAIN

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Christopher Zdyrski

Research Professional

University of Georgia

UNITED STATES

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Rachel A. Allbaugh

UNITED STATES

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Lionel Sebbag

ISRAEL

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John Bonagura

Emeritus Professor

Ohio State University

UNITED STATES

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Jonathan Mochel

Research Interests

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Recent Grants

Articles (20)

A Preclinical Model to Assess Intestinal Barrier Integrity Using Canine Enteroids and Colonoids

Penicillin and Gentamicin Concentrations in the Uterine Fluid of Non‐Pregnant Mares Following a Single Intrauterine Infusion

Optimizing First‐Line Therapeutics in Non‐Small Cell Lung Cancer: Insights From Joint Modeling and Large‐Scale Data Analysis

Evolving value and validity of animal models in veterinary therapeutic research: Impact of scientific progress

Retrospective Evaluation of Complications Associated With Surgically Placed Gastrostomy Tubes in Dogs (2010-2020): 133 Cases.

Cisplatin-Induced Metabolic Responses Measured with Raman Spectroscopy in Cancer Cells, Spheroids, and Canine-Derived Organoids

University of Georgia College of Veterinary Medicine's Precision One Health Initiative improves animal and human health by developing alternative models of disease.

Evaluating the Bias of Two Point-of-Care Glucometers for Calves and Ewes: Awareness for Ruminant Practitioners

Pharmacokinetics of isavuconazonium sulfate and its active metabolite isavuconazole in healthy dogs.

Population Pharmacokinetics and Absolute Oral Bioavailability of Lasalocid after Single Intravenous and Intracrop Administration in Laying Hens.

Effect of the Probiotic <i>Bacillus subtilis</i> DE-CA9<sup>TM</sup> on Fecal Scores, Serum Oxidative Stress Markers and Fecal and Serum Metabolome in Healthy Dogs

Blood product usage and factors associated with transfusions in cats with hemoperitoneum: 33 cases (2018-2022).

Increased drug concentration and repeated eye drop administration as strategies to optimize topical drug delivery: A fluorophotometric study in healthy dogs

OrganoidChip facilitates hydrogel-free immobilization for fast and blur-free imaging of organoids.

Changes of Enterocyte Morphology and Enterocyte:Goblet Cell Ratios in Dogs with Protein-Losing and Non-Protein-Losing Chronic Enteropathies

Echocardiographic caudal vena cava measurements in healthy cats and in cats with congestive heart failure and non-cardiac causes of cavitary effusions.

Canine Intestinal Organoids as a Novel In Vitro Model of Intestinal Drug Permeability: A Proof-of-Concept Study

Comparison of Traditional Didactic vs. Additional Hands-on Simulation Training in the Performance of Basic Life Support in Veterinary Students - A Prospective, Blinded, Randomized Study.

Exploring the secrets of super-aging: a UK Biobank study on brain health and cognitive function.

Understanding the background and clinical significance of the WHO, WOAH, and EMA classifications of antimicrobials to mitigate antimicrobial resistance.

Collaborators (10)

Dipak Kumar Sahoo

Teresa C. DeFrancesco

David Meyerholz

Pierre‐Yves Mulon

Lara Barron

David Díaz-Regañón Fernández

Christopher Zdyrski

Rachel A. Allbaugh

Lionel Sebbag

John Bonagura

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