Jonathan Schertzer

Associate Professor

McMaster University Faculty of Health Sciences

Canada

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About

Jonathan Schertzer is an Associate Professor at McMaster University Faculty of Health Sciences in Canada. His research focuses on the interplay between gut microbiota and metabolic diseases, with recent articles addressing topics such as the effects of hyperglycemia on gut infections and the implications of intermittent fasting on metabolic flexibility. He actively explores the connections between inflammation, metabolic health, and microbiota, contributing to advancements in understanding obesity and related disorders.

Articles (23)

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2025

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Collaborators (7)

Gregory Steinberg

Professor

McMaster University

CANADA

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Alba Santiago

Vall d'Hebron Institute of Oncology

SPAIN

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Alison C. Holloway

CANADA

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Daniel Marko

McMaster University

CANADA

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Elena Verdu

Professor

McMaster University

CANADA

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Katherine M Morrison

McMaster University

CANADA

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Wolfram Ruf

GERMANY

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Jonathan Schertzer

Research Interests

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About

Articles (23)

Not So Fast: Intermittent Fasting Fails to Improve Metabolic Flexibility in Mice With Obesity and Type 2 Diabetes

Microbiota protect against frailty and loss of skeletal muscle, and maintain inflammatory tone during aging in mice

Food supply toxicants and additives alter the gut microbiota and risk of metabolic disease

Hyperglycemia worsens gut bacterial infection through intestinal Wnt, but independent of endotoxemia or obesity

A Bead‐Based Quantum Dot Immunoassay Integrated with Multi‐Module Microfluidics Enables Real‐Time Multiplexed Detection of Blood Insulin and Glucagon

A Bead‐Based Quantum Dot Immunoassay Integrated with Multi‐Module Microfluidics Enables Real‐Time Multiplexed Detection of Blood Insulin and Glucagon (Adv. Sci. 29/2025)

Gut substrate trap of D-lactate from microbiota improves blood glucose and fatty liver disease in obese mice

NOD1 promotes leukocyte clearance and limits inflammation in female mice during obesity‐associated acute lung injury

GDF15 links adipose tissue lipolysis with anxiety

Postbiotic Impact on Host Metabolism and Immunity Provides Therapeutic Potential in Metabolic Disease

Bruton’s tyrosine kinase (BTK) inhibitors alter blood glucose and insulin in obese mice but reduce inflammation independent of BTK

Intermittent fasting influences immunity and metabolism

Intermittent fasting increases fat oxidation and promotes metabolic flexibility in lean mice but not obese type 2 diabetic mice

Wearable Aptalyzer Integrates Microneedle and Electrochemical Sensing for In Vivo Monitoring of Glucose and Lactate in Live Animals

Crohn’s disease proteolytic microbiota enhances inflammation through PAR2 pathway in gnotobiotic mice

Microbiota and Nod-like receptors balance inflammation and metabolism during obesity and diabetes

Obesity promotes a leaky gut, inflammation and pre-diabetes by lowering gut microbiota that metabolise ethanolamine

Associations of intrapartum antibiotics and growth, atopy, gastrointestinal and sleep outcomes at one year of age

Correction To: Associations of intrapartum antibiotics and growth, atopy, gastrointestinal and sleep outcomes at one year of age

Dietary Nitrate and Corresponding Gut Microbiota Prevent Cardiac Dysfunction in Obese Mice.

Does Obesity or Hyperglycemia Alter Metabolic Endotoxemia?

Interferon regulatory factor 4 dictates metabolic flexibility of fat versus muscle loss during repeated intermittent fasting

Statins activate the NLRP3 inflammasome and inhibit the Hippo pathway to promote myopathy

Collaborators (7)

Gregory Steinberg

Alba Santiago

Alison C. Holloway

Daniel Marko

Elena Verdu

Katherine M Morrison

Wolfram Ruf

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