João Espregueira‐Mendes

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Recent Grants

Grant: Close

Biomaterials and Additive Manufacturing: Osteochondral Scaffold innovation applied to osteoarthritis

Open Date: 2017-01-01

Close Date: 2021-01-01

Grant: Close

Projecto Estratégico - LA 26 - 2013-2014

Open Date: 2013-01-01

Close Date: 2014-01-01

Grant: Close

ICVS/3B’s - Laboratório Associado, Instituto de Ciências da Vida e da Saúde / Grupo de Investigação em Biomateriais, Biodegradaveis e Biomiméticos

Open Date: 2013-01-01

Close Date: 2015-01-01

Grant: Close

Projecto Estratégico - LA 26 - 2013-2014

Open Date: 2013-01-01

Close Date: 2014-01-01

Grant: Close

Projecto Estratégico - LA 26 - 2011-2

Open Date: 2011-01-01

Close Date: 2012-01-01

Articles (11)

Purpose Patellofemoral instability (PFI) is a common condition that can be caused from multiple factors, including lower limb rotational malalignments. Determining precise criteria for performing corrective torsional osteotomy can be a daunting task due to the lack of consensus on normal and excessive values and the limited evidence‐based data in the postoperative results. The purpose was to assess the clinical, functional and imaging outcomes following derotational distal femoral osteotomy (DDFO) in patients with PFI and/or anterior knee pain (AKP) associated with lower limb rotational malalignments. Methods Searches were conducted on PubMed, EMBASE and Web of Science databases up to October 2023. Studies reporting outcomes after DDFO in patients with PFI and/or AKP were eligible for the systematic review. The primary outcome was imaging metrics, especially femoral anteversion. Secondary outcomes included the patient‐reported outcome measures (PROMs) (clinical and functional). Quantitative synthesis involved the use of weighted averages to calculate pre‐ to postoperative mean differences (MD) and compare them against the minimal clinically important difference (MCID). Results Ten studies (309 knees) were included with a mean follow‐up of 36.1 ± 11.7 months. Imaging outcomes consistently indicated the correction of femoral anteversion (MD = −19.4 degrees, 95% confidence interval: −20.1 to −18.7) following DDFO. PROMs showed significant improvements in most studies, exceeding the MCID. Patient satisfaction with the DDFO was high (93.3%). Conclusions The DDFO was an effective treatment option for correcting excessive femoral anteversion in patients with PFI associated with clinically relevant functional and clinical improvement and a high satisfaction rate. Level of Evidence Level IV, systematic review of level II–IV studies.

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2024

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2023

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2023

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2023

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2023

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2023

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2022

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2022

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2021

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2021

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2021

Collaborators (4)

Marco P. L. Parente

-

PORTUGAL
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Cristiana Branco da Cunha

Head Of Business Development

Stemmatters (Portugal)

PORTUGAL
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Rui L. Reis

University of Minho

PORTUGAL
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Patrício Costa

Universidade do Porto Faculdade de Medicina

PORTUGAL
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