José Manuel Fernández-Fernández
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Professor Agregat (Tenured Assistant Professor)
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About
José Manuel Fernández-Fernández is a Tenured Assistant Professor at Universitat Pompeu Fabra, Spain. His research focuses on the genetic and molecular mechanisms underlying neurodegenerative diseases, including amyloid beta-peptide toxicity and calcium signaling in health and aging. He has contributed to significant studies on atrial fibrillation, microRNA regulation, and the effects of rare genetic mutations on ataxia and neurodevelopmental deficits.
Recent Grants
Grant: Close
HYPOGLYCOSYLATION OF CaV2.1 AND PIEZO CHANNELS: NEW PATHOLOGICAL MECHANISMS AND THERAPEUTIC TARGETS FOR NEUROLOGICAL DISORDERS IN PHOSPHOMANNOMUTASE 2 DEFICIENCY
Open Date: 2019-01-01
Close Date: 2022-12-01
Grant: Close
Low-throughput evaluation of novel, selective CaV2.1 inhibitors in animal models of Familial Hemiplegic Migraine: modulation of excitatory neurotransmission and analysis of potential therapeutic value.
Open Date: 2018-01-01
Close Date: 2019-12-01
Grant: Close
MECHANO/OSMOSENSITIVE CHANNELS IN EPITHELIA, CANCER AND ASTHMA
Open Date: 2016-01-01
Close Date: 2018-12-01
Grant: Close
Identification of novel, selective voltage-gated CaV2.1 calcium channel inhibitors which reverse the gain of channel function produced by Hemiplegic Migraine CACNA1A mutations
Open Date: 2015-02-01
Close Date: 2016-12-01
Grant: Close
Identification of new molecular determinants controlling the function of voltage-gated Ca2+ and K+ channels in physiology and pathology
Open Date: 2013-01-01
Close Date: 2015-12-01
Articles (7)
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2023
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2021
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2021
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2021
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2021
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2021
Year:
2020
Collaborators (3)
Rubén Vicente García
Associate Professor
Universitat Pompeu Fabra
Muñoz Francisco
Profesor
Universitat Pompeu Fabra
Mercè Izquierdo-Serra
Lecturer
Universitat Autònoma de Barcelona Facultat de Medicina
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