Jose de Leon

Washington University in Saint Louis School of Medicine

United States

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Articles (19)

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Collaborators (2)

Georgios Schoretsanitis

University of Zurich

SWITZERLAND

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Edoardo Spina

University of Messina

ITALY

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Jose de Leon

Research Interests

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Articles (19)

The clozapine package inserts need to reflect lower doses for Asians

Interindividual variability in olanzapine steady‐state concentrations in Chinese: exploring single nucleotide polymorphisms of metabolic enzymes

Evaluating the adverse drug reactions to clozapine in populations of children and adolescents: insights from VigiBase data

Clozapine-treated patients and myocardial infarction in adults: a pharmacovigilance study in VigiBase interpreted in the context of the literature

Clozapine for older adults with severe mental illness: a systematic review and expert recommendations for clinical practice

Nifedipine May Be an Inhibitor of Clozapine Metabolism as Seen in 5 Patients: 2 From a US Double-Blind Study and 3 From a German Therapeutic Drug Monitoring Study

Clozapine pharmacovigilance in Croatia: Underreporting of specific adverse drug reactions and excellent reporting of suicide attempts

Letter to the FDA Proposing Major Changes in the US Clozapine Package Insert Supported by Clozapine Experts Worldwide. Part I

Letter to the FDA Proposing Major Changes in the US Clozapine Package Insert Supported by Clozapine Experts Worldwide. Part II

Clozapine may consistently protect from suicidal behaviors while other antipsychotics may lack a specific protective effect: a comprehensive VigiBase study interpreted in the context of the prior literature

How can we better address the pharmacokinetics of antipsychotics in children and adolescents?

Investigating in VigiBase over 6000 cases of pneumonia in clozapine-treated patients in the context of the literature: focus on high lethality and the association with aspiration pneumonia

Population pharmacokinetics of olanzapine in pediatric patients with psychiatric disorders

Proposing a novel approach for the long-term use of monthly paliperidone palmitate: adjusting injection dose versus adjusting injection interval

Implications of psychological reactance for clinical practice in psychiatry including a systematic review.

A Chinese medicine called Danggui Longhui may be a new clinically relevant clozapine inducer: Two case reports identified by therapeutic drug monitoring

Clozapine-associated pericarditis and pancreatitis in children and adolescents: A systematic literature review and pharmacovigilance study using the VigiBase database

The introduction of clozapine at the Nathan Kline Institute in New York and its long-term consequences

Can Slow Personalized Titration Using C-Reactive Protein Monitoring Decrease the High Rates and Mortality of Clozapine-Associated Myocarditis Seen in Some Countries? A Call for Research

Collaborators (2)

Georgios Schoretsanitis

Edoardo Spina

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