Jose V. Castell

Emeritus Professor

University of Valencia

Spain

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About

Jose V. Castell is an Emeritus Professor at the University of Valencia, Spain. His research encompasses drug-induced liver injury, hepatotoxicity, and metabolomics, as highlighted in his recent publications. He focuses on the mechanisms of liver diseases, including non-alcoholic fatty liver disease and drug-induced fatty liver disease, employing various analytical methodologies to enhance understanding and prediction of liver pathology.

Articles (14)

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2025

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Teresa Delgado

BioCruces Health research Institute

SPAIN

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Jose V. Castell

Research Interests

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Articles (14)

The acyl glucuronide of 2-(4-diethylamino-2-hydroxybenzoyl)benzoic acid: Synthesis, structural assignment, occurrence as a human phase II metabolite of Uvinul® A Plus and acute aquatic toxicity

Drug-Induced Fatty Liver Disease (DIFLD): A Comprehensive Analysis of Clinical, Biochemical, and Histopathological Data for Mechanisms Identification and Consistency with Current Adverse Outcome Pathways

Exploring Individual Variability in Drug-Induced Liver Injury (DILI) Responses through Metabolomic Analysis

Cluster-Partial Least Squares (c-PLS) regression analysis: Application to miRNA and metabolomic data

Gut Microbiota and Plasma Bile Acids Associated with Non-Alcoholic Fatty Liver Disease Resolution in Bariatric Surgery Patients

Metabolomics-based strategy to assess drug hepatotoxicity and uncover the mechanisms of hepatotoxicity involved

Methionine Cycle Rewiring by Targeting miR-873-5p Modulates Ammonia Metabolism to Protect the Liver from Acetaminophen

Quantitative Prediction of Steatosis in Patients with Non-Alcoholic Fatty Liver by Means of Hepatic MicroRNAs Present in Serum and Correlating with Hepatic Fat

Modeling a Novel Variant of Glycogenosis IXa Using a Clonal Inducible Reprogramming System to Generate “Diseased” Hepatocytes for Accurate Diagnosis

The Potential Role of Metabolomics in Drug-Induced Liver Injury (DILI) Assessment

Extracting consistent biological information from functional results of metabolomic pathway analysis using the Mantel's test

Metabolomic analysis to discriminate drug-induced liver injury (DILI) phenotypes

The in vitro assessment of the toxicity of volatile, oxidisable, redox-cycling compounds: phenols as an example

Comparing Targeted vs. Untargeted MS2 Data-Dependent Acquisition for Peak Annotation in LC–MS Metabolomics

Collaborators (6)

Arkaitz Carracedo

Salvador Gil

Miguel A. Miranda

RAMIRO JOVER

Francisco Javier Cubero

Teresa Delgado

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