Josef Köhrle

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Seniorprofessor

Charité - Universitätsmedizin Berlin

Germany

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Josef Köhrle is a Seniorprofessor at Charite-Universitätsmedizin Berlin, Germany. His research primarily focuses on endocrinology, particularly in the areas of thyroid hormone metabolism and hormone health. Recent publications include studies on deiodinase inhibitors, thyroid treatments, and the impacts of endocrine-disrupting chemicals.

Recent Grants

Grant: Close

Strategien zur Erhöhung der lokalen T3-Konzentration in der Leber

Open Date: 2020-07-01

Close Date: 2024-06-01

Grant: Close

ATHENA „Assays for the identification of Thyroid Hormone axis-disrupting chemicals: Elaborating Novel Assessment strategies”.

Open Date: 2019-01-01

Close Date: 2023-12-01

Grant: Close

Z-Project: Analytical procedures for the determination of the thyroid hormone status in biological samples collected in the framework of the priority programme SPP 1629

Open Date: 2012-01-01

Close Date:

Grant: Close

Z-Project: Analytical procedures for the determination of the thyroid hormone status in biological samples collected in the framework of the priority programme SPP 1629

Open Date: 2012-01-01

Close Date:

Grant: Close

Effects of thyronamines (TAM) and thyroacetic acid (TAC) metabolites on energy metabolism, mitochondrial function, Ca2+-signalling, plasma membrane action

Open Date: 2012-01-01

Close Date:

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2022

Collaborators (11)

Eddy Rijntjes

Charité - Universitätsmedizin Berlin

GERMANY

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Marta Axelstad Petersen

Technical University of Denmark

DENMARK

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Ulrich Schweizer

Universitätsklinikum Bonn

GERMANY

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Pauliina Damdimopoulou

Professor of Reproductive Biology

Karolinska Institutet

SWEDEN

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Lutz Schomburg

GERMANY

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Andrea di Fonzo

Italian Institute of Technology

ITALY

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Wenzel Schöning

Charité - Universitätsmedizin Berlin

GERMANY

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Eva Katrin Wirth

GERMANY

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Jérôme Bertherat

FRANCE

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Martina Rauner

GERMANY

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Angel Nadal

Professor of Physiology

Universidad Miguel Hernández de Elche

SPAIN

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Josef Köhrle

Research Interests

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About

Recent Grants

Articles (21)

Identification and Characterization of Highly Potent and Isoenzyme-Selective Inhibitors of Deiodinase Type I via a Nonradioactive High-Throughput Screening Method

For a better global hormone health!

ETA GUIDELINES FOR THE USE OF LEVOTHYROXINE SODIUM PREPARATIONS IN MONOTHERAPY TO OPTIMIZE THE TREATMENT OF HYPOTHYROIDISM.

Hyperthyroidism-driven bone loss depends on BMP receptor Bmpr1a expression in osteoblasts

Identification of Human TRIAC Transmembrane Transporters

Endocrine disrupting chemicals are a threat to hormone health: a commentary on behalf of the ESE.

Response to Fitzgerald et al. re: “Thyroid Stimulating Hormone and Thyroid Hormones (Triiodothyronine and Thyroxine): An American Thyroid Association-Commissioned Review of Current Clinical and Laboratory Status”

Low thyroxine serves as an upstream regulator of ecophysiological adaptations in Ansell's mole-rats.

Strong associations of serum selenoprotein P with all-cause mortality and mortality due to cancer, cardiovascular, respiratory and gastrointestinal diseases in older German adults.

The ETA-ESE statement on the European Chemicals Agency opinion on iodine as an endocrine disruptor.

Structural Insights into the Iodothyronine Deiodinase 2 Catalytic Core and Deiodinase Catalysis and Dimerization

Hepatic Energy Metabolism under the Local Control of the Thyroid Hormone System.

Clinical Interpretation of Thyroid Tests: Considerations for Reference Intervals

Selenium, Iodine and Iron–Essential Trace Elements for Thyroid Hormone Synthesis and Metabolism

Comparative analysis of thyroid hormone systems in rodents with subterranean lifestyle.

Deiodinases control local cellular and systemic thyroid hormone availability

3,5-T2-an Endogenous Thyroid Hormone Metabolite as Promising Lead Substance in Anti-Steatotic Drug Development?

Changes in Thyroid Metabolites after Liothyronine Administration: A Secondary Analysis of Two Clinical Trials That Incorporated Pharmacokinetic Data

100 YEARS OF VITAMIN D: Light and health: a century after the therapeutic use of UV light and vitamin D, hormones advanced medical care

Perinatal exposure to the thyroperoxidase inhibitors methimazole and amitrole perturbs thyroid hormone system signaling and alters motor activity in rat offspring

Seizures, ataxia and parvalbumin-expressing interneurons respond to selenium supply in Selenop-deficient mice.

Collaborators (11)

Eddy Rijntjes

Marta Axelstad Petersen

Ulrich Schweizer

Pauliina Damdimopoulou

Lutz Schomburg

Andrea di Fonzo

Wenzel Schöning

Eva Katrin Wirth

Jérôme Bertherat

Martina Rauner

Angel Nadal

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