Joseph Deweese

Professor of Biochemistry

United States

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About

Joseph Deweese is a Professor of Biochemistry at Freed-Hardeman University in the United States. His research primarily focuses on the study of topoisomerases, particularly the human DNA Topoisomerase IIα, including its structural and biochemical properties, and the impact of intrinsically disordered domains on its catalytic activity. Recent publications reflect his interests in the intersection of science and faith, indicating a commitment to exploring ethical considerations in scientific education.

Articles (12)

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2025

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2025

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2024

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2024

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2023

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2023

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2022

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2022

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2022

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2021

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2021

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2020

Collaborators (2)

Adam Wilson

Associate Professor

Rush University

UNITED STATES

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Neil Osheroff

Vanderbilt University School of Medicine

UNITED STATES

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Joseph Deweese

Research Interests

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About

Articles (12)

Evaluating AlphaFold 3 Folding of the Intrinsically Disordered Human DNA Topoisomerase IIα C-Terminal Domain

Mutagenesis of Intrinsically Disordered Domain Impacts Topoisomerase IIα Catalytic Activity

Bioinformatic Analysis of Topoisomerase IIα Reveals Interdomain Interdependencies and Critical C-Terminal Domain Residues

Faith and facts: Exploring the intersection of religion and science among anatomy educators

No Time to Relax and Unwind: Exploration of Topoisomerases and a Growing Field of Study

Inhibition of Topoisomerases by Metal Thiosemicarbazone Complexes

Structural and Biochemical Basis of Etoposide-Resistant Mutations in Topoisomerase IIα

A model for incorporating faith, values, and ethics into a healthcare provider course

PSICalc: a novel approach to identifying and ranking critical non-proximal interdependencies within the overall protein structure

Cannabidiol oxidation product HU-331 is a potential anticancer cannabinoid-quinone: a narrative review

Exploration of the Role of the C-Terminal Domain of Human DNA Topoisomerase IIα in Catalytic Activity

Synthesis and evaluation of etoposide and podophyllotoxin analogs against topoisomerase IIα and HCT-116 cells.

Collaborators (2)

Adam Wilson

Neil Osheroff

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