Joseph Dias

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DISC: Dupuytren’s Interventions Surgery vs. Collagenase. A pragmatic multi-centre randomised controlled non-inferiority cost effectiveness trial comparing injections of collagenase into the cord to surgical correction in the treatment of moderate Dupuytren’s contracture in adult patients

Open Date: 2016-11-01

Close Date: 2022-10-31

Grant: Close

Scaphoid Waist Internal Fixation for Fractures Trial (SWIFFT) Cast treatment versus surgical fixation of fractures of the Scaphoid waist in adults: a Multi-centre Randomised Controlled Trial

Open Date: 2013-04-01

Close Date: 2022-10-01

Grant: Close

Scaphoid Waist Internal Fixation for Fractures Trial (SWIFFT)Cast treatment versus surgical fixation of fractures of the Scaphoid waist in adults: –a Multi-centre Randomised Controlled Trial

Open Date: 2013-04-01

Close Date: 2022-03-31

Articles (12)

Year:

2023

Year:

2023

Aims There is ambiguity surrounding the degree of scaphoid union required to safely allow mobilization following scaphoid waist fracture. Premature mobilization could lead to refracture, but late mobilization may cause stiffness and delay return to normal function. This study aims to explore the risk of refracture at different stages of scaphoid waist fracture union in three common fracture patterns, using a novel finite element method. Methods The most common anatomical variant of the scaphoid was modelled from a CT scan of a healthy hand and wrist using 3D Slicer freeware. This model was uploaded into COMSOL Multiphysics software to enable the application of physiological enhancements. Three common waist fracture patterns were produced following the Russe classification. Each fracture had differing stages of healing, ranging from 10% to 90% partial union, with increments of 10% union assessed. A physiological force of 100 N acting on the distal pole was applied, with the risk of refracture assessed using the Von Mises stress. Results Overall, 90% to 30% fracture unions demonstrated a small, gradual increase in the Von Mises stress of all fracture patterns (16.0 MPa to 240.5 MPa). All fracture patterns showed a greater increase in Von Mises stress from 30% to 10% partial union (680.8 MPa to 6,288.6 MPa). Conclusion Previous studies have suggested 25%, 50%, and 75% partial union as sufficient for resuming hand and wrist mobilization. This study shows that 30% union is sufficient to return to normal hand and wrist function in all three fracture patterns. Both 50% and 75% union are unnecessary and increase the risk of post-fracture stiffness. This study has also demonstrated the feasibility of finite element analysis (FEA) in scaphoid waist fracture research. FEA is a sustainable method which does not require the use of finite scaphoid cadavers, hence increasing accessibility into future scaphoid waist fracture-related research. Cite this article: Bone Jt Open 2023;4(8):612–620.

Year:

2023

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2023

Year:

2023

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2023

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2023

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2023

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2022

Year:

2022

Year:

2022

Year:

2022

Collaborators (6)

Chris Peach

Professor

Manchester University NHS Foundation Trust

UNITED KINGDOM
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Nick johnson

University Hospitals of Derby and Burton NHS Foundation Trust

UNITED KINGDOM
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Michael R Whitehouse

-

UNITED KINGDOM
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Matthew L. Costa

University of Oxford

UNITED KINGDOM
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Alexander Ooms

University of Oxford

UNITED KINGDOM
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Juul Achten

University of Oxford

UNITED KINGDOM
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