Joshua Leonard

Associate Professor

Northwestern University

United States

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Joshua Leonard is an Associate Professor at Northwestern University, USA. His research primarily focuses on synthetic biology, with recent studies on engineered receptors, synthetic biosensors, and extracellular vesicle engineering. He is recognized for his work in utilizing computational modeling to enhance biological system characterization and the targeted delivery of therapeutics.

Articles (17)

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2025

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2021

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2021

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UNITED STATES

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Julius Lucks

Professor

Northwestern University

UNITED STATES

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Joshua Leonard

Research Interests

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Articles (17)

Conversion of natural cytokine receptors into orthogonal synthetic biosensors

Exploring Structure—Function Relationships in Engineered Receptor Performance Using Computational Structure Prediction

Enhancing extracellular vesicle cargo loading and functional delivery by engineering protein-lipid interactions

HaloTag display enables quantitative single‐particle characterisation and functionalisation of engineered extracellular vesicles

Deconstructing synthetic biology across scales: a conceptual approach for training synthetic biologists

Building Synthetic Biosensors Using Red Blood Cell Proteins

Comparative Evaluation of Synthetic Cytokines for Enhancing Production and Performance of NK92 Cell-Based Therapies

Genetically encoding multiple functionalities into extracellular vesicles for the targeted delivery of biologics to T cells

GAMES: A Dynamic Model Development Workflow for Rigorous Characterization of Synthetic Genetic Systems

Correction to “GAMES: A Dynamic Model Development Workflow for Rigorous Characterization of Synthetic Genetic Systems”

Elucidating Design Principles for Engineering Cell‐Derived Vesicles to Inhibit SARS‐CoV‐2 Infection

Fighting fire with fire: deploying complexity in computational modeling to effectively characterize complex biological systems

The evolution of synthetic receptor systems

Model-guided design of mammalian genetic programs

Control of mammalian cell-based devices with genetic programming

Computation-guided optimization of split protein systems

Nanofountain Probe Electroporation Enables Versatile Single‐Cell Intracellular Delivery and Investigation of Postpulse Electropore Dynamics

Collaborators (7)

Yogesh Goyal

Niall Mangan

Neha Kamat

Ludmilla Aristilde

Joseph J. Muldoon

Ashty Karim

Julius Lucks

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