Joshua Pajak

University of Massachusetts Chan Medical School

United States

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Articles (10)

Year:

2025

Year:

2024

Year:

2024

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2023

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2022

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2022

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2022

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2021

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2021

Year:

2021

Collaborators (6)

Ye Zhou

Duke University

UNITED STATES

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Brendan Hilbert

Scorpion Therapeutics (United States)

UNITED STATES

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Paul Jardine

Professor

University of Minnesota

UNITED STATES

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Gaurav Arya

Duke University

UNITED STATES

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Mark White

University of Texas Medical Branch at Galveston

UNITED STATES

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Christl Gaubitz

DENMARK

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Joshua Pajak

Research Interests

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Articles (10)

Regulation of the ordinal DNA translocation cycle in bacteriophage Φ29 through trans-subunit interactions

The mechano-chemistry of a viral genome packaging motor

Differences between bacteria and eukaryotes in clamp loader mechanism, a conserved process underlying DNA replication

Conformational dynamics control assembly of an extremely long bacteriophage tail tube

Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader

Redox-sensitive E2 Rad6 controls cellular response to oxidative stress via K63-linked ubiquitination of ribosomes

Molecular dynamics of DNA translocation by FtsK

A viral genome packaging motor transitions between cyclic and helical symmetry to translocate dsDNA

Viral packaging ATPases utilize a glutamate switch to couple ATPase activity and DNA translocation

Atomistic basis of force generation, translocation, and coordination in a viral genome packaging motor

Collaborators (6)

Ye Zhou

Brendan Hilbert

Paul Jardine

Gaurav Arya

Mark White

Christl Gaubitz

Make your next move.