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Juan Botas

Professor

Baylor College of Medicine

United States

Research Interests

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About

Juan Botas is an Associate Professor at Baylor College of Medicine in the United States. His research interests focus on neurodegenerative diseases, specifically the roles of huntingtin and tau proteins in cellular processes. Recent articles authored by Dr. Botas explore innovative methodologies for studying molecular signatures in the brain, as well as the interactions of mutant proteins with various compounds.

Articles (12)

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2026

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2025

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2025

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2025

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2025

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2025

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2025

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2023

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2023

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Northwestern University Feinberg School of Medicine

UNITED STATES

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Juan Botas

Research Interests

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About

Articles (12)

Genetic analysis of the X-linked adrenoleukodystrophy gene ABCD1 in Drosophila uncovers a conserved phenotype

Multi-epitope immunocapture of huntingtin reveals striatum-selective molecular signatures

MeCP2 Interacts with the Super Elongation Complex to Regulate Transcription

Longitudinal multi-omics in alpha-synuclein <i>Drosophila</i> model discriminates disease- from age-associated pathologies in Parkinson's disease

Computational and functional prioritization identifies genes that rescue behavior and reduce tau protein in fly and human cell models of Alzheimer disease

Modeling the effects of Huntington's disease on age-related genes reveals CXXC4 as an epigenetic target to restore health and excitability of Drd1-expressing striatal neurons

Progressive Remodeling of Global Protein Interaction Networks in a Mouse Model of Tauopathy

Revealing the nervous system requirements of Alzheimer disease risk genes in<i> Drosophila</i>

SPA-STOCSY: an automated tool for identifying annotated and non-annotated metabolites in high-throughput NMR spectra

Tau polarizes an aging transcriptional signature to excitatory neurons and glia

Integration of transcriptome-wide association study with neuronal dysfunction assays provides functional genomics evidence for Parkinson’s disease genes

Suppression of toxicity of the mutant huntingtin protein by its interacting compound, desonide

Collaborators (6)

Ann Moser

Janice L. Brissette

Benjamin Wolozin

Eric Dammer

Oguz Kanca

Yuki Aoi

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