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Juan Carlos Morales

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Full Research Professor

Instituto de Parasitología y Biomedicina López-Neyra

Spain

Research Interests

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Professors in Spain Professors in Pharmaceutical Chemistry Pharmaceutical Chemistry professors in Spain

Recent Grants

Grant: Open

DNA G-quadruplex as therapeutic target: new ligands based on pyrvinium as anticancer and anti-infective agents

Open Date: 2026-04-01

Close Date: 2029-03-01

Grant: Open

DNA/RNA G-quadruplexes as new therapeutic targets: synthesis, evaluation and mode of action of ligands as potential drugs with a look into the antiviral activity

Open Date: 2025-09-01

Close Date: 2028-08-01

Grant: Close

DNA G-quadruplex as targets in oncology and infectious diseases: design, synthesis and evaluation of ligands as potential drugs

Open Date: 2022-09-01

Close Date: 2025-08-01

Grant: Close

New drugs based on resveratrol derivatives for the treatment of retina degenerative diseases

Open Date: 2020-06-26

Close Date: 2023-06-30

Grant: Close

Carbohydrate-DNA Interactions: new DNA base pairs as lego pieces on nanoassemblies and DNA G-quadruplex ligands as therapeutic agents

Open Date: 2019-01-01

Close Date: 2022-09-01

Articles (16)

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Collaborators (17)

ELENA GONZALEZ-REY

Principal Research Scientist

Instituto de Parasitología y Biomedicina López-Neyra

SPAIN

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Valentina Pirota

Assistant Professor (RTD-A)

University of Pavia

ITALY

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Tom Desmet

Prof.

Ghent University

BELGIUM

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M. VIOLANTE DE PAZ

Full Professor

Universidad de Sevilla

SPAIN

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Francisco J Diaz-Corrales

Group Leader. Retinal Neurodegeneration and Advanced Therapies

Andalusian Molecular Biology and Regenerative Medicine Centre

SPAIN

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Ricardo Lucas

Profesor Titular de Universidad

Universidad de Sevilla

SPAIN

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Filippo Doria

Associate Professor

University of Pavia

ITALY

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Juan tolosa

Profesor Contratado Doctor Interino

University of Castilla-La Mancha

SPAIN

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M. Carmen Galan

Academic , Professor of Organic and Biological Chemistry

University of Bristol

UNITED KINGDOM

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Francisca Vicente Perez

AREA HEAD SCREENING & TARGET VALIDATION (retired)

Fundación MEDINA

SPAIN

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Efres Belmonte Reche

Universidad de Granada

SPAIN

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Oscar P. Kuipers

University of Groningen

NETHERLANDS

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Susana P. G. Costa

University of Minho

PORTUGAL

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Maria Manuela Marques Raposo

Full Professor

University of Minho

PORTUGAL

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Julia Castillo-González

Post-doctoral researcher

Instituto de Parasitología y Biomedicina López-Neyra

SPAIN

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Mario Delgado

Full Professor and Director of Institute

Consejo Superior de Investigaciones Cientificas

SPAIN

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Francisco Javier Villadiego Luque

Associate Professor

Universidad de Sevilla

SPAIN

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Juan Carlos Morales

Research Interests

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Recent Grants

Articles (16)

Microwave-assisted synthesis of new triangulenium dyes for lifetime imaging microscopy (FLIM)

Extending Thioflavin T Fluorescence Probe to 2-Ethenyl-benzothiazole Derivatives: Drug-like Quadruplex Ligands with Potent Antitrypanosomatid Activity

Beyond antiparasitic activity: elucidating the antibacterial potency of pyrvinium pamoate

Cortistatin as a Novel Multimodal Therapy for the Treatment of Parkinson’s Disease

Designing Antitrypanosomal and Antileishmanial BODIPY Derivatives: A Computational and In Vitro Assessment

Structure–Activity Study on Substituted, Core-Extended, and Dyad Naphthalene Diimide G-Quadruplex Ligands Leading to Potent Antitrypanosomal Agents

Oligostyrylbenzene Derivatives with Antiparasitic and Antibacterial Activity as Potent G-Quadruplex Ligands

Synthesis and Evaluation of Glucosyl-, Acyl- and Silyl- Resveratrol Derivatives as Retinoprotective Agents: Piceid Octanoate Notably Delays Photoreceptor Degeneration in a Retinitis Pigmentosa Mouse Model

A yeast-based high-throughput screen identifies inhibitors of trypanosomatid HRG heme transporters with potent leishmanicidal and trypanocidal activity

Piceid Octanoate Protects Retinal Cells against Oxidative Damage by Regulating the Sirtuin 1/Poly-ADP-Ribose Polymerase 1 Axis In Vitro and in rd10 Mice

DNA G-quadruplexes in the genome of Trypanosoma cruzi as potential therapeutic targets for Chagas disease: Dithienylethene ligands as effective antiparasitic agents

Hydroxytyrosyl punicate: A first overview of a novel phenolipid with antiproliferative and antitrypanosomal activity

Identification of new antioxidant drugs in a human in vitro model of ageing-associated cataract

Probing the binding and antiparasitic efficacy of azobenzene G-quadruplex ligands to investigate G4 ligand design

Synthesis and antimicrobial activity of aminoalkyl resveratrol derivatives inspired by cationic peptides

Polyaromatic Bis(indolyl)methane Derivatives with Antiproliferative and Antiparasitic Activity

Collaborators (17)

ELENA GONZALEZ-REY

Valentina Pirota

Tom Desmet

M. VIOLANTE DE PAZ

Francisco J Diaz-Corrales

Ricardo Lucas

Filippo Doria

Juan tolosa

M. Carmen Galan

Francisca Vicente Perez

Efres Belmonte Reche

Oscar P. Kuipers

Susana P. G. Costa

Maria Manuela Marques Raposo

Julia Castillo-González

Mario Delgado

Francisco Javier Villadiego Luque

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