Julia E. Neumann

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Prof. Dr. med.

University Medical Center Hamburg-Eppendorf

Germany

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About

Prof. Dr. med. Julia E. Neumann is a faculty member at the University Medical Center Hamburg-Eppendorf in Germany. Her research areas include the integration of omic data for large-scale analyses, molecular classification of tumors, and the investigation of protein patterns in neurodevelopmental disorders. Recent publications highlight her work on transposable elements in tumor subtypes, clinical biomarkers in glioblastoma, and the use of computational methods for data integration in omics datasets.

Recent Grants

Grant: Close

Deciphering the gene expression signature of Human Endogenous Retroviruses in malignant embryonal brain tumors - new potential targets for diagnosis and therapy

Open Date: 2022-01-01

Close Date: 2024-01-01

Grant: Close

The role of LIN28A in brain development and pediatric brain tumors

Open Date: 2020-03-01

Close Date: 2026-03-01

Articles (20)

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Collaborators (9)

Ulrich Schüller

University Medical Center Hamburg-Eppendorf

GERMANY

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Hartmut Schluter

University Professor

University Medical Center Hamburg-Eppendorf

GERMANY

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Jorg Tatzelt

Professor/ head of department

Ruhr-Universität Bochum Medizinische Fakultät

GERMANY

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Helena Radbruch

Charité - Universitätsmedizin Berlin

GERMANY

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Juliette Hukin

Clinical Associate Professor

The University of British Columbia

CANADA

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Fausto Rodriguez

University of California, Los Angeles

UNITED STATES

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Christian Thomas

University Hospital Münster

GERMANY

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Hermann Altmeppen

University Medical Center Hamburg-Eppendorf (UKE)

GERMANY

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Olivera Casar-Borota

Associate Professor

SWEDEN

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Julia E. Neumann

Research Interests

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About

Recent Grants

Articles (20)

Outcome-associated factors in a molecularly defined cohort of central neurocytoma.

Spatial proteomics reveals distinct protein patterns in cortical migration disorders caused by LIN28A overexpression and WNT activation.

High performance data integration for large-scale analyses of incomplete Omic profiles using Batch-Effect Reduction Trees (BERT)

Expression of LTR and LINE1 transposable elements defines atypical teratoid/rhabdoid tumor subtypes

Extracellular Vesicles Carrying Tenascin-C are Clinical Biomarkers and Improve Tumor-Derived DNA Analysis in Glioblastoma Patients

HarmonizR: blocking and singular feature data adjustment improve runtime efficiency and data preservation.

Computational Methods for Data Integration and Imputation of Missing Values in Omics Datasets

Cleavage site-directed antibodies reveal the prion protein in humans is shed by ADAM10 at Y226 and associates with misfolded protein deposits in neurodegenerative diseases

Morphology‐based molecular classification of spinal cord ependymomas using deep neural networks

Multiomic profiling of medulloblastoma reveals subtype-specific targetable alterations at the proteome and N-glycan level.

Low‐grade diffusely infiltrative tumour (LGDIT), SMARCB1‐mutant: A clinical and histopathological distinct entity showing epigenetic similarity with ATRT‐MYC

HarmonizR enables data harmonization across independent proteomic datasets with appropriate handling of missing values

Spatial molecular profiling of a central nervous system low‐grade diffusely infiltrative tumour with INI1 deficiency featuring a high‐grade atypical teratoid/rhabdoid tumour component

Overexpression of Lin28A in neural progenitor cells in vivo does not lead to brain tumor formation but results in reduced spine density

Co-activation of Sonic hedgehog and Wnt signaling in murine retinal precursor cells drives ocular lesions with features of intraocular medulloepithelioma

An atypical teratoid/rhabdoid tumor (AT/RT) with molecular features of pleomorphic xanthoastrocytoma (PXA) in a 62-year-old patient

Histopathological patterns in atypical teratoid/rhabdoid tumors are related to molecular subgroup

Molecular diagnostics helps to identify distinct subgroups of spinal astrocytomas.

Correction to: Mutations within FGFR1 are associated with superior outcome in a series of 83 diffuse midline gliomas with H3F3A K27M mutations

The genetic landscape of choroid plexus tumors in children and adults.

Collaborators (9)

Ulrich Schüller

Hartmut Schluter

Jorg Tatzelt

Helena Radbruch

Juliette Hukin

Fausto Rodriguez

Christian Thomas

Hermann Altmeppen

Olivera Casar-Borota

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