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Up to 30% off — ends 7 Aug

ONLY00h00m00s

Jun Nakayama

Osaka International Cancer Institute

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Research Interests

Cell Biology

Pharmacology

Cancer Biology

Tyrosine Kinase

Targeted Therapy

Tumor Microenvironment

Tumor Immunology

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Recent Grants

Grant: Close

Verification of "DCIS to IDC hypothesis" and search for DCIS diagnostic markers

Open Date: 2021-04-01

Close Date: 2023-03-01

Grant: Close

Analysis of Cancer Evolution by Single Cell Amplicomics

Open Date: 2020-04-01

Close Date: 2023-03-01

Grant: Close

Research for the mechanism of late relapse in breast cancer

Open Date: 2019-06-01

Close Date: 2020-03-01

Grant: Close

Multi-Organ Metastasis of Breast Cancer Regulated by ERBB2-Amplicon

Open Date: 2018-04-01

Close Date: 2021-03-01

Articles25

Collaborators6

Nao Nishida-Aoki

Assistant Professor

Waseda University

Tomohiko Taguchi

Tohoku University

Kosuke Yoshida

Nagoya University

Kentaro Semba

Waseda University

Hirotaka Koga

Osaka University

Koji Okamoto

Teikyo University

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Jun Nakayama

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Research Interests

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Recent Grants

Articles25

Single‐Nucleus RNA Sequencing and Spatial Transcriptomics for Squamous Cell Carcinoma Arising From Ovarian Mature Teratoma

<scp>KLHL5</scp> Contributes to Colorectal Cancer Cell Survival by Promoting Cell Cycle Progression and Suppressing Apoptotic Cell Death

Implication of <scp>KLHL</scp> Gene Family Member <scp>KLHL5</scp> in Colorectal Cancer Progression and Prognosis

Cell biological insights into human STING variants

Targeting TREX1 induces innate immune response in drug-resistant Small Cell Lung Cancer

Aberrant regulation of serine metabolism drives extracellular vesicle release and cancer progression

Analysis of the responsiveness to antiandrogens in multiple breast cancer cell lines

Astrocyte-induced mGluR1 activates human lung cancer brain metastasis via glutamate-dependent stabilization of EGFR

Targeting DHX9 triggers tumor-intrinsic interferon response and replication stress in Small Cell Lung Cancer.

Nuclear receptor profiling for subtype classification and as prognostic markers in 33 cancer types

Investigation of Tumor Heterogeneity Using Integrated Single-Cell RNA Sequence Analysis to Focus on Genes Related to Breast Cancer-, EMT-, CSC-, and Metastasis-Related Markers in Patients with HER2-Positive Breast Cancer

Osteoblast‐derived extracellular vesicles exert osteoblastic and tumor‐suppressive functions via <scp>SERPINA3</scp> and <scp>LCN2</scp> in prostate cancer

Targeting c-Jun is a potential therapy for luminal breast cancer bone metastasis

Aberrant accumulation of NIK promotes tumor growth by dysregulating translation and post-translational modifications in breast cancer

Downregulation of miR‑10b‑5p facilitates the proliferation of uterine leiomyosarcoma cells: A microRNA sequencing‑based approach

HOXB7 induces STAT3-mediated transformation and lung metastasis in immortalized mammary gland NMuMG cells.

Metastatic potentials classified with hypoxia‐inducible factor 1 downstream genes in pan‐cancer cell lines

Collagen induction of immune cells in the mammary glands during pregnancy

PPP1R12A is a recycling endosomal phosphatase that facilitates YAP activation

Spatial exosome analysis using cellulose nanofiber sheets reveals the location heterogeneity of extracellular vesicles

Cancer-prone Phenotypes and Gene Expression Heterogeneity at Single-cell Resolution in Cigarette-smoking Lungs

Anomalous Epithelial Variations and Ectopic Inflammatory Response in Chronic Obstructive Pulmonary Disease.

Single-Cell Transcriptome Profiling Reveals Intratumoral Heterogeneity and Molecular Features of Ductal Carcinoma In Situ.

Identification of two cancer stem cell-like populations in triple-negative breast cancer xenografts.

Aberrant activation of cell cycle-related kinases and the potential therapeutic impact of PLK1 or CHEK1 inhibition in uterine leiomyosarcoma.

Collaborators6

Nao Nishida-Aoki

Tomohiko Taguchi

Kosuke Yoshida

Kentaro Semba

Hirotaka Koga

Koji Okamoto

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