Junko Matsuzaki

Research Professor

University of Chicago

United States

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Junko Matsuzaki is a Research Professor at The University of Chicago, United States. Her research primarily focuses on immunotherapy and its implications for cancer treatment, with recent articles exploring mTOR inhibition, T cell receptor signaling, and the role of memory CD8 + T cells in various cancers. She examines the mechanisms of tumor immunity and the development of targeted cellular therapies, particularly in ovarian and lung cancers.

Articles (12)

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2025

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2024

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2023

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2022

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2022

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2022

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2022

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2022

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2022

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2021

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2021

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2021

Collaborators (7)

Fumito Ito

Associate Professor of Surgery

University of Southern California

UNITED STATES

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Scott Olejniczak

Assistant Professor of Oncology

Roswell Park Comprehensive Cancer Center

UNITED STATES

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Mark Long

Assistant Professor of Oncology

Roswell Park Comprehensive Cancer Center

UNITED STATES

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Ryutaro Kajihara

Kumamoto University

JAPAN

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Takemasa Tsuji

Research Associate Professor

University of California Davis Comprehensive Cancer Center

UNITED STATES

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Sudharshan Ravi

University of Zurich

SWITZERLAND

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Melissa A. Geller

University of Minnesota

UNITED STATES

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Junko Matsuzaki

Research Interests

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Articles (12)

mTOR inhibition modulates vaccine-induced immune responses to generate memory T cells in patients with solid tumors

NK Receptor Signaling Lowers TCR Activation Threshold, Enhancing Selective Recognition of Cancer Cells by TAA-Specific CTLs

Predictive and Prognostic Implications of Circulating CX3CR1+ CD8+ T Cells in Non–Small Cell Lung Cancer Patients Treated with Chemo-Immunotherapy

Identification of Claudin 6-specific HLA class I- and HLA class II-restricted T cell receptors for cellular immunotherapy in ovarian cancer

Loss-of-function of the hippo transducer TAZ reduces mammary tumor growth through a myeloid-derived suppressor cell-dependent mechanism.

Tissue residency of memory CD8<sup>+</sup> T cells matters in shaping immunogenicity of ovarian cancer.

Tcf-1 protects anti-tumor TCR-engineered CD8<sup>+</sup> T-cells from GzmB mediated self-destruction.

Recombinant human Hsp110-gp100 chaperone complex vaccine is nontoxic and induces response in advanced stage melanoma patients.

Metabolic adaptation of ovarian tumors in patients treated with an IDO1 inhibitor constrains antitumor immune responses.

CXCR6 by increasing retention of memory CD8+ T cells in the ovarian tumor microenvironment promotes immunosurveillance and control of ovarian cancer.

GEN-1 in Combination with Neoadjuvant Chemotherapy for Patients with Advanced Epithelial Ovarian Cancer: A Phase I Dose-Escalation Study.

Stimulation of an anti-tumor immune response with “chromatin-damaging” therapy

Collaborators (7)

Fumito Ito

Scott Olejniczak

Mark Long

Ryutaro Kajihara

Takemasa Tsuji

Sudharshan Ravi

Melissa A. Geller

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