Justin Hwang

Assistant Professor

University of Minnesota

United States

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About

Justin Hwang is an Assistant Professor at the University of Minnesota, USA. His current research focuses on cancer biology, including chronic NK cell activation, tumorigenicity in breast cancer, and the molecular mechanisms underlying colorectal cancer and prostate cancer. He recently published articles exploring the implications of immune cell interactions, the role of genetic alterations in cancer outcomes, and the effects of SARS-CoV-2 infection on immunocompromised patients.

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Collaborators (20)

Anwaar Saeed

University of Pittsburgh

UNITED STATES

Justin Hwang

Research Interests

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About

Articles (30)

Chronic NK cell activation results in a dysfunctional, tissue resident-like state mediated by KLF2 deficiency

CREB5 promotes tumorigenicity and upregulates druggable cell surface modalities in basal-like breast cancer

SARS-CoV-2 infection drives local inflammation of the intestinal epithelium in immunocompromised patients with cancer

Dissecting the functional differences and clinical features of R-spondin family members in metastatic prostate cancer.

Uncovering PD-L1 among immune cell predictive biomarkers and actionable genetic alterations in anal squamous-cell carcinomas in the era of immunotherapy.

<i>HSD3B1</i> (c.1100C) Genotype Is Associated with Distinct Tumoral and Clinical Outcomes in Breast and Endometrial Cancers

The Influence of the Germline <i>HSD3B1</i> Adrenal-Permissive Allele (c.1100 C) on the Somatic Alteration Landscape, the Transcriptome, and Immune Cell Infiltration in Prostate Cancer

Germline-Somatic Interactions in BRCA-Associated Cancers: Unique Molecular Profiles and Clinical Outcomes Linking ATM to TP53 Synthetic Essentiality

Comparative transcriptomics reveals a mixed basal, club, and hillock epithelial cell identity in castration-resistant prostate cancer

Deciphering Colorectal Cancer–Hepatocyte Interactions: A Multiomics Platform for Interrogation of Metabolic Crosstalk in the Liver–Tumor Microenvironment

Unraveling the Global Proteome and Phosphoproteome of Prostate Cancer Patient-Derived Xenografts

Current uses and resistance mechanisms of enzalutamide in prostate cancer treatment

Androgen production, uptake, and conversion (APUC) genes define prostate cancer patients with distinct clinical outcomes

MYBL2 Drives Prostate Cancer Plasticity: Inhibiting its Transcriptional Target CDK2 for RB1-Deficient Neuroendocrine Prostate Cancer.

Targeting the multifaceted BRAF in cancer: New directions

Epigenomic signatures of sarcomatoid differentiation to guide the treatment of renal cell carcinoma

Exploring the differences in the tumor microenvironment and immuno-oncologic targets in pancreatic ductal adenocarcinomas (PDAC) according to KRAS mutational status

Pan-Cancer Interrogation of B7-H3 (CD276) as an Actionable Therapeutic Target across Human Malignancies

Genomic Profiling of Rare Undifferentiated Sarcomatoid Subtypes of Pancreatic Carcinomas: In Search of Therapeutic Targets

Natural Killer Cell Infiltration in Prostate Cancers Predict Improved Patient Outcomes

Editorial: Hormone resistance in cancer

Unique spectrum of activating <i>BRAF</i> alterations in prostate cancer

Nicotinamide enhances natural killer cell function and yields remissions in patients with non-Hodgkin lymphoma.

Saracatinib synergizes with enzalutamide to downregulate AR activity in CRPC

Metastatic Prostate Cancers with <i>BRCA2</i> versus <i>ATM</i> Mutations Exhibit Divergent Molecular Features and Clinical Outcomes

ALAN is a computational approach that interprets genomic findings in the context of tumor ecosystems.

ZBTB7A as a novel vulnerability in neuroendocrine prostate cancer

Integrative molecular analyses define correlates of high B7-H3 expression in metastatic castrate-resistant prostate cancer

VRK1 as a synthetic lethal target in VRK2-methylated cancers of the nervous system

Regulatory genes in the Androgen Production, Uptake, and Conversion (APUC) pathway in advanced prostate cancer

Collaborators (20)

Anwaar Saeed

Yinjie Qiu

Pedro Barata

Akhilesh Kumar

Patrycja Puchalska

Dang Nguyen

Roddy S. O'Connor

Tanya Freedman

Julie Ostrander

Sandra Safo

Frank Cichocki

Veronika Bachanova

Emmanuel Stylianos Antonarakis

Yousef Zakharia

Carly Miller

Braedan McCluskey

Jonathan So

Justin M. Drake

Melissa A. Geller

R. Stephanie Huang

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