Justin Legleiter

Associate Professor

West Virginia University

United States

Research Interests

Explore related searches

Professors in United States

Contact this professor

Get a free first email built on one of their papers, ready for you to edit and send yourself.

About

Justin Legleiter is an Associate Professor at West Virginia University, USA. His research focuses on the aggregation of huntingtin proteins and their impact on lipid membranes, as well as the physicochemical properties that influence these interactions. Recent publications include studies on the toxicity of huntingtin aggregates in Caenorhabditis elegans and the structure characterization of disordered peptides using advanced mass spectrometry techniques.

Articles (15)

Year:

2025

Year:

2025

Year:

2025

Year:

2025

Year:

2024

Year:

2023

Year:

2022

Year:

2022

Year:

2022

Year:

2021

Year:

2021

Year:

2020

Year:

2020

Year:

2020

Year:

2020

Collaborators (2)

Jeffrey Comer

Assistant Professor

University of Kansas

UNITED STATES

View details

JOHN M. TOMICH

Professor

University of Kansas

UNITED STATES

View details

ApplyKite TwinLearns as you apply

Make your next move.

Prepare your application

Review drafts before you send them.

Justin Legleiter

Research Interests

Explore related searches

Contact this professor

About

Articles (15)

Exogenous Huntingtin-Exon1 Aggregates Exhibit Distinct Levels of Toxicity to Caenorhabditis elegans

Membranes as targets and modifiers of mutant huntingtin aggregation

Amyloidogenic SARS-CoV-2 Spike Protein-Derived Peptides Form Oligomers and Selectively Damage Lipid Membranes

Structure Characterization of a Disordered Peptide Using In-Droplet Hydrogen/Deuterium Exchange Mass Spectrometry and Molecular Dynamics

The polyglutamine domain is the primary driver of seeding in huntingtin aggregation

Cholesterol impacts the formation of huntingtin/lipid complexes and subsequent aggregation

Design of Peptides that Fold and Self-Assemble on Graphite

Oxidation Promotes Distinct Huntingtin Aggregates in the Presence and Absence of Membranes

Physicochemical Properties Altered by the Tail Group of Lipid Membranes Influence Huntingtin Aggregation and Lipid Binding

Macromolecular crowding in solution alters huntingtin interaction and aggregation at interfaces

Huntingtin Protein Purification and Experimentation: An Innovative Undergraduate Research-Based Biochemistry Experiment

Phosphomimetic Mutations Impact Huntingtin Aggregation in the Presence of a Variety of Lipid Systems

Normalizing polydiacetylene colorimetric assays of vesicle binding across lipid systems

SUMOylation Prevents Huntingtin Fibrillization and Localization onto Lipid Membranes

Nucleation Inhibition of Huntingtin Protein (htt) by Polyproline PPII Helices: A Potential Interaction with the N-Terminal α-Helical Region of Htt

Collaborators (2)

Jeffrey Comer

JOHN M. TOMICH

Make your next move.