Kai-Lieh Huang

Research assistant professor

University of Rochester

United States

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Dr. Kai-Lieh Huang is a Research Assistant Professor at the University of Rochester, USA. His research focuses on alternative polyadenylation, the Integrator complex, and mRNA turnover, with implications for developmental ciliopathies and gene regulation. Recent articles authored by Dr. Huang explore topics such as the role of inositol hexakisphosphate in Integrator function and quantitative trait loci associated with complex trait heritability.

Articles (6)

Year:

2023

Year:

2022

Year:

2022

Year:

2021

Year:

2020

Year:

2020

Collaborators (3)

Ya Cui

University of California, Irvine

UNITED STATES

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Vincenzo Gennarino

Assistant Professor

Columbia University Irving Medical Center

UNITED STATES

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Karen Adelman

Professor

Harvard Medical School

UNITED STATES

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Kai-Lieh Huang

Research Interests

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Articles (6)

Alternative polyadenylation alters protein dosage by switching between intronic and 3'UTR sites.

INTS13 variants causing a recessive developmental ciliopathy disrupt assembly of the Integrator complex

Inositol hexakisphosphate is required for Integrator function

An atlas of alternative polyadenylation quantitative trait loci contributing to complex trait and disease heritability

Integrator Recruits Protein Phosphatase 2A to Prevent Pause Release and Facilitate Transcription Termination

Tob2 phosphorylation regulates global mRNA turnover to reshape transcriptome and impact cell proliferation

Collaborators (3)

Ya Cui

Vincenzo Gennarino

Karen Adelman

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