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Kalesh Karunakaran A

Teesside University

United Kingdom

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Research Interests

Biochemistry

70%

Cell Biology

40%

Leishmania

50%

Protein Chemistry

40%

Proteostasis

40%

Metaproteomics

30%

Parasitology

20%

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Recent Grants

Grant: Close

ProbesPTRM

Open Date: 2012-07-01

Close Date: 2014-06-01

Articles16

Alpha-synuclein aggregation induces prominent cellular lipid changes as revealed by Raman spectroscopy and machine learning analysis

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Year:

2025

Molecular Insights into α-Synuclein Fibrillation

Article Link

Year:

2025

Profiling Serine Hydrolases in the Leishmania Host–Pathogen Interactome Using Cell‐Permeable Activity‐Based Fluorophosphonate Probes

Article Link

Year:

2025

Nucleoside Analogues for Chagas Disease and Leishmaniasis Therapy: Current Status and Future Perspectives

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Year:

2024

BONCAT-iTRAQ Labelling Reveals Molecular Markers of Adaptive Responses in Toxoplasma gondii to Pyrimethamine Treatment

Article Link

Year:

2024

Inhibition of HSP90 distinctively modulates the global phosphoproteome of Leishmania mexicana developmental stages

Article Link

Year:

2023

Navigating drug repurposing for Chagas disease

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Year:

2023

Transcriptome-Wide Identification of Coding and Noncoding RNA-Binding Proteins Defines the Comprehensive RNA Interactome of Leishmania mexicana

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Year:

2022

Discovery of Leishmania Druggable Serine Proteases by Activity-Based Protein Profiling

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Year:

2022

Antileishmanial Drug Development: A Review of Modern Molecular Chemical Tools and Research Strategies

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Year:

2021

Quantitative Proteomics Reveals that Hsp90 Inhibition Dynamically Regulates Global Protein Synthesis in Leishmania mexicana

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Year:

2021

Affinity‐based proteomics reveals novel targets of inositol pyrophosphate (5‐IP 7 )‐dependent phosphorylation and binding in Trypanosoma cruzi replicative stages

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Year:

2020

Defeating the trypanosomatid trio: proteomics of the protozoan parasites causing neglected tropical diseases

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Year:

2020

Defeating the trypanosomatid trio: Proteomics of the protozoan parasites causing neglected tropical diseases

Article Link

Year:

2020

Detectives and helpers: Natural products as resources for chemical probes and compound libraries

Article Link

Year:

2020

How can proteomics overhaul our understanding of Leishmania biology?

Article Link

Year:

2020

Collaborators15

Ehmke Pohl

University of Durham

UNITED KINGDOM

Fawaz Aldabbagh

Professor of Medicinal & Pharmaceutical Chemistry

Kingston University

UNITED KINGDOM

Lucy Butler

Teesside University

UNITED KINGDOM

Ojodomo John Achadu

Teesside University

UNITED KINGDOM

Brian Suarez Mantilla

Assistant Professor (Research)

University of Durham

UNITED KINGDOM

Meez Islam

Professor of Physical Chemistry

Teesside University

UNITED KINGDOM

Annalisa Occhipinti

Teesside University

UNITED KINGDOM

P. G. Steel

University of Durham

UNITED KINGDOM

Anutthaman Parthasarathy

Lecturer in Microbiology

University of Bradford

UNITED KINGDOM

Nathaniel Brown

Lecturer

Stanford University

UNITED STATES

Ahmad Khundakar

Senior Lecturer

Teesside University

UNITED KINGDOM

Paul Denny

Professor

University of Durham

UNITED KINGDOM

Chaimaa Tarzi

Teesside University

UNITED KINGDOM

Wenbin Wei

Chief Experimental Officer (bioinformatics)

University of Durham

UNITED KINGDOM

Claudio Angione

Professor

Teesside University

UNITED KINGDOM

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