Karen P. Steel

King’s College London

United Kingdom

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Articles (14)

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2025

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2025

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2025

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2022

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2022

Collaborators (6)

Simon Waddington

Professor of Gene Therapy

University College London

UNITED KINGDOM

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Jing Chen

King’s College London

UNITED KINGDOM

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Neil Jon Ingham

King’s College London

UNITED KINGDOM

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MIGUEL ANGEL MORENO-PELAYO

HEAD OF DEPARTMENT

HOSPITAL UNIVERSITARIO RAMÓN Y CAJAL

SPAIN

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Bebiana Da Costa Sousa

Aston University

UNITED KINGDOM

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Giulia Soldà

Associate professor Professor in Cellular and Experimental Biology

Humanitas University

ITALY

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Karen P. Steel

Research Interests

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Articles (14)

Non-invasive testing to diagnose the underlying auditory pathology of hearing impairment

The importance of accurate phenotyping in large-scale analyses of common disorders such as hearing loss

Low level of expression of known deafness genes Kcne1, Kcnj10 or Col4a3 is sufficient to maintain hearing in mice

Two new mouse alleles of Ocm and Slc26a5

A new mutation of Sgms1 causes gradual hearing loss associated with a reduced endocochlear potential

Targeted genome editing restores auditory function in adult mice with progressive hearing loss caused by a human microRNA mutation.

Rescue of cochlear vascular pathology prevents sensory hair cell loss in Norrie disease

Systemic gene therapy rescues retinal dysfunction and hearing loss in a model of Norrie disease

Reversal of an existing hearing loss by gene activation in Spns2 mutant mice

Insights into the pathophysiology of DFNA44 hearing loss associated with CCDC50 frameshift variants

Accurate phenotypic classification and exome sequencing allow identification of novel genes and variants associated with adult-onset hearing loss.

In-depth genetic and molecular characterization of diaphanous related formin 2 (DIAPH2) and its role in the inner ear.

The Effect of a Pex3 Mutation on Hearing and Lipid Content of the Inner Ear

Investigating the characteristics of genes and variants associated with self-reported hearing difficulty in older adults in the UK Biobank.

Collaborators (6)

Simon Waddington

Jing Chen

Neil Jon Ingham

MIGUEL ANGEL MORENO-PELAYO

Bebiana Da Costa Sousa

Giulia Soldà

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