Karen Wilcox

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Chair/Professor

University of Utah

United States

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About

Professor Karen Wilcox serves as the Chair at the University of Utah in the United States. Her research primarily focuses on epilepsy, specifically exploring antiseizure medications and their effects in various models, including Dravet syndrome. Recent articles highlight her work on EEG signal dimensions as indices of seizure propensity, the development of preclinical testing platforms for epilepsy therapies, and the evaluation of prototype antiseizure drugs.

Recent Grants

Grant: Close

IGF::OT::IGF OTHER FUNCTIONS NINDS EPILEPSY THERAPY SCREENING PROGRAM

Open Date: 2016-09-30

Close Date: 2017-09-29

Grant: Close

IGF::OT::IGF OTHER FUNCTIONS NINDS EPILEPSY THERAPY SCREENING PROGRAM

Open Date: 2016-09-30

Close Date: 2018-09-29

Grant: Close

ADD PROGRAM SYMPOSIUM

Open Date: 2015-04-01

Close Date: 2016-03-31

Grant: Close

Calcium Signaling in a Model of Temporal Lobe Epilepsy

Open Date: 2012-09-30

Close Date: 2018-06-30

Grant: Close

A Novel Mouse Model of Temporal Lobe Epilepsy

Open Date: 2011-08-01

Close Date: 2015-04-30

Articles (13)

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2025

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2025

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2024

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2024

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2022

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2022

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2021

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2021

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2021

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2021

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2020

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2020

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2020

Collaborators (5)

Ana Beatriz DePaula-Silva

Assistant Professor

University of Utah

UNITED STATES

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Joseph Rower

Research Assistant Professor

University of Utah Health

UNITED STATES

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Melissa Barker‐Haliski

UNITED STATES

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Annamaria Vezzani

Head of Experimental Neurology Laboratory

Istituto di Ricerche Farmacologiche Mario Negri

ITALY

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Cameron S. Metcalf

University of Utah

UNITED STATES

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Karen Wilcox

Research Interests

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About

Recent Grants

Articles (13)

EEG signal dimension is an index of seizure propensity and antiseizure medication effects in a mouse model of acquired epilepsy

Development of a preclinical testing platform for clinically relevant therapy for Dravet syndrome

Intracerebral delivery of antiseizure medications by microinvasive neural implants

Utilizing an acute hyperthermia‐induced seizure test and pharmacokinetic studies to establish optimal dosing regimens in a mouse model of Dravet syndrome

Evaluating the efficacy of prototype antiseizure drugs using a preclinical pharmacokinetic approach

Screening of prototype antiseizure and anti‐inflammatory compounds in the Theiler's murine encephalomyelitis virus model of epilepsy

Inflammation Unleashed in Viral-Induced Epileptogenesis

Development of an antiepileptogenesis drug screening platform: Effects of everolimus and phenobarbital

Development of an antiseizure drug screening platform for Dravet syndrome at the NINDS contract site for the Epilepsy Therapy Screening Program

Response: Usefulness of the post‐kainate spontaneous recurrent seizure model for screening for antiseizure and for neuroprotective effects

Reactivity and increased proliferation of NG2 cells following central nervous system infection with Theiler’s murine encephalomyelitis virus

Evaluation of subchronic administration of antiseizure drugs in spontaneously seizing rats

The current approach of the Epilepsy Therapy Screening Program contract site for identifying improved therapies for the treatment of pharmacoresistant seizures in epilepsy

Collaborators (5)

Ana Beatriz DePaula-Silva

Joseph Rower

Melissa Barker‐Haliski

Annamaria Vezzani

Cameron S. Metcalf

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