Karl G. Wagner

Professor

University of Bonn

Germany

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About

Karl G. Wagner is a Professor at the University of Bonn in Germany. His research primarily focuses on pharmaceutical sciences, including drug delivery systems, nanoparticle formulation, and evaluation of bioactive compounds. Recent publications include studies on inhalation therapy, granulation techniques, and multivariate analysis for drug-polymer compatibility. He is actively contributing to advancements in continuous manufacturing and optimizing drug release properties.

Articles (20)

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2025

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2022

Collaborators (5)

Michael Gütschow

University of Bonn

GERMANY

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Christian Steinebach

University of Bonn

GERMANY

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Martin Kuentz

University of Applied Sciences and Arts Northwestern Switzerland

SWITZERLAND

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Diana Imhof

W3 Professor for Pharmaceutical Biochemistry and Bioanalytics

Rheinische Friedrich-Wilhelms-Universität Bonn

GERMANY

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Toni Kühl

University of Bonn

GERMANY

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Karl G. Wagner

Research Interests

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About

Articles (20)

High dose dry powder inhalation of itraconazole nanocrystals: Impact of drug load and inhalation device

Rational design and DoE based prediction model for levodopa gastroretentive systems based on hot-melt tube extrusion

Phytochemical Profile, Acute, and Subacute Toxicity of Spray‐Dried Hydroethanolic Extract From <i>Punica granatum</i> Leaves

High loading of lipophilic compounds in mesoporous silica for improved solubility and dissolution performance

Powder dosing within continuous manufacturing: A lean approach for gravimetric dosing configuration and equipment selection

Effect of Liquid Load Level and Binder Type on the Tabletability of Mesoporous Silica Based Liquisolids

Optimizing release properties of tablets from Spondias mombin spray-dried leaves extract using dry and melt granulation

Multivariate Analysis of Solubility Parameters for Drug-Polymer Miscibility Assessment in Preparing Raloxifene Hydrochloride Amorphous Solid Dispersions

In vivo predictive dissolution of the lipophilic phytochemicals trans-resveratrol, coenzyme Q10 and quercetin

Evaluation of Printability of PVA-Based Tablets from Powder and Assessment of Critical Rheological Parameters

Impact of process stress on protein stability in highly-loaded solid protein/PEG formulations from small-scale melt extrusion

Advanced In Vivo Prediction by Introducing Biphasic Dissolution Data into PBPK Models

Amorphous Solid Dispersions Layered onto Pellets—An Alternative to Spray Drying?

Micro-Scale Vacuum Compression Molding as a Predictive Screening Tool of Protein Integrity for Potential Hot-Melt Extrusion Processes

Direct Tableting on a Continuous Manufacturing Line—Impact of Mixing Parameters, Material Densities, and Drug Load on Subsequent Process Parameters and Tablet Quality

Solubility Enhanced Formulation Approaches to Overcome Oral Delivery Obstacles of PROTACs

Boost of solubility and supersaturation of celecoxib via synergistic interactions of methacrylic acid-ethyl acrylate copolymer (1:1) and hydroxypropyl cellulose in ternary amorphous solid dispersions

Pharmacokinetics and Pharmacodynamics (PK/PD) of Corallopyronin A against Methicillin-Resistant <i>Staphylococcus aureus</i>

Bioanalytical Workflow for Qualitative and Quantitative Assessment of Hot-Melt Extruded Lysozyme Formulations

Pharmacology and early ADMET data of corallopyronin A, a natural product with macrofilaricidal anti-wolbachial activity in filarial nematodes

Collaborators (5)

Michael Gütschow

Christian Steinebach

Martin Kuentz

Diana Imhof

Toni Kühl

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