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Katherine Donovan

Senior Scientist

Dana-Farber Cancer Institute

United States

Research Interests

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Articles (20)

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2026

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Collaborators (18)

Ralitsa Radostinova Madsen

Independent Investigator

MRC Protein Phosphorylation and Ubiquitylation Unit

UNITED KINGDOM

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Roman Sarott

Max Planck Research Group Leader

Max Planck Institute for Medical Research

GERMANY

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Aurélien Dugourd

Senior Staff Scientist

European Bioinformatics Institute

UNITED KINGDOM

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Panagiotis Karagiannis

Dana-Farber Cancer Institute

UNITED STATES

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Franziska Wachter

Harvard University

UNITED STATES

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Stephen Hinshaw

Stanford University

UNITED STATES

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Radosław Nowak

Professor

University of Bonn

GERMANY

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Priscilla Yang

Professor

Stanford University

UNITED STATES

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Muhammad Murtaza Hassan

Assistant Professor

University of Virginia

UNITED STATES

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Eric S. Fischer

Director

Harvard Medical School

UNITED STATES

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Zuzanna Kozicka

Tenure-Track Assistant Professor

EPFL (École Polytechnique Fédérale de Lausanne)

SWITZERLAND

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Jaron Mercer

Assistant Professor

University of California, Santa Cruz

UNITED STATES

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Hai-Tsang Huang

Senior Research Scientist I

Broad Institute

UNITED STATES

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Steven Corsello

Stanford University

UNITED STATES

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Nathanael S. Gray

Stanford University

UNITED STATES

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Jevon Cutler

Assistant Professor

Oregon Health & Science University

UNITED STATES

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Nicolas Thoma

Senior Group Leader

Friedrich Miescher Institute

SWITZERLAND

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Dennis Gillingham

University of Basel

SWITZERLAND

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Katherine Donovan

Research Interests

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Articles (20)

Charged molecular glue discovery enabled by targeted degron display.

Degraders of the dengue virus capsid protein exhibit differentiated pharmacology relative to capsid inhibitors.

Degron-independent recruitment of KAT2A expands the target space of CRBN molecular glues

Development of FBXO22 Degraders and the Recruitment Ligand 2-Pyridinecarboxyaldehyde (2-PCA)

Discovery of BRD9 Molecular Glue Degraders That Spare Cardiomyocytes

Niclosamide: CRL4AMBRA1 mediated degradation of cyclin D1 following mitochondrial membrane depolarization

Development of Potent and Selective CK1α Molecular Glue Degraders

Mezigdomide is effective alone and in combination with menin inhibition in preclinical models of KMT2A-r and NPM1c AML

Design principles for cyclin K molecular glue degraders

Continuous evolution of compact protein degradation tags regulated by selective molecular glues

Ubiquitin-specific proximity labeling for the identification of E3 ligase substrates

Discovery of CRBN-Dependent WEE1 Molecular Glue Degraders from a Multicomponent Combinatorial Library

Broad-spectrum activity against mosquito-borne flaviviruses achieved by a targeted protein degradation mechanism

Author Correction: Targeting DCAF5 suppresses SMARCB1-mutant cancer by stabilizing SWI/SNF

Targeting DCAF5 suppresses SMARCB1-mutant cancer by stabilizing SWI/SNF

Multiomic profiling of breast cancer cells uncovers stress MAPK-associated sensitivity to AKT degradation

HDAC6/aggresome processing pathway importance for inflammasome formation is context-dependent

Covalent Stapling of the Cereblon Sensor Loop Histidine Using Sulfur-Heterocycle Exchange

Chemical Specification of E3 Ubiquitin Ligase Engagement by Cysteine-Reactive Chemistry.

Proteolysis-targeting chimeras with reduced off-targets

Collaborators (18)

Ralitsa Radostinova Madsen

Roman Sarott

Aurélien Dugourd

Panagiotis Karagiannis

Franziska Wachter

Stephen Hinshaw

Radosław Nowak

Priscilla Yang

Muhammad Murtaza Hassan

Eric S. Fischer

Zuzanna Kozicka

Jaron Mercer

Hai-Tsang Huang

Steven Corsello

Nathanael S. Gray

Jevon Cutler

Nicolas Thoma

Dennis Gillingham

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