Kathryn Burns

University of Auckland

New Zealand

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Articles (18)

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2025

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2021

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2021

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2021

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2021

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2021

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2020

Collaborators (5)

Nuala Helsby

NEW ZEALAND

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Stephen Alexander

Associate Professor

University of Nottingham

UNITED KINGDOM

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Malcolm Tingle

Head of School

University of Auckland

NEW ZEALAND

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Janak de Zoysa

Associate Professor

University of Auckland

NEW ZEALAND

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Robert Matthew Strother

Senior Clinical Lecturer

University of Otago Christchurch

NEW ZEALAND

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Kathryn Burns

Research Interests

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Articles (18)

A thymine-challenge test to prospectively evaluate dihydropyrimidine dehydrogenase activity for risk of severe 5-fluorouracil-induced gastrointestinal toxicity

Acute exposure to clozapine and sodium valproate impairs oxidative phosphorylation in human cardiac mitochondria

CYP-catalysed cycling of clozapine and clozapine- N -oxide promotes the generation of reactive oxygen species in vitro

Clozapine metabolism and cardiotoxicity: A prospective longitudinal study

Cytochrome P450 in GtoPdb v.2023.1

Cytochrome P450 in GtoPdb v.2023.1

The Concise Guide to PHARMACOLOGY 2023/24: Enzymes

Intracellular activation of 4-hydroxycyclophosphamide into a DNA-alkylating agent in human leucocytes.

Severe 5-Fluorouracil-Associated Gastrointestinal Toxicity Unexplained by Dihydropyrimidine Dehydrogenase Deficiency and Renal Impairment: Should We Be Investigating Other Elimination Pathways to Assess the Risk of 5-Fluorouracil Toxicity?

Cyclophosphamide bioactivation pharmacogenetics in breast cancer patients

CYP2 family: physiological enzymes subset in GtoPdb v.2021.2

Cytochrome P450 in GtoPdb v.2021.2

Comparison of a thymine challenge test and endogenous uracil–dihydrouracil levels for assessment of fluoropyrimidine toxicity risk

A systematic review of inter-individual differences in the DNA repair processes involved in melphalan monoadduct repair in relation to treatment outcomes

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Enzymes

Severe 5-Fluorouracil-Associated Gastrointestinal Toxicity Unexplained by Dihydropyrimidine Dehydrogenase Deficiency and Renal Impairment: Should We Be Investigating Other Elimination Pathways to Assess the Risk of 5-Fluorouracil Toxicity?

Cyclophosphamide bioactivation pharmacogenetics in breast cancer patients

Circulating microRNA as biomarkers of clozapine-induced cardiotoxicity

Collaborators (5)

Nuala Helsby

Stephen Alexander

Malcolm Tingle

Janak de Zoysa

Robert Matthew Strother

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