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Kathy Niakan

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The Francis Crick Institute

United Kingdom

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Genetic approaches to studying early lineage specification in human embryos

Open Date: 2021-08-01

Close Date: 2026-07-31

Articles (21)

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Collaborators (29)

Panagiotis Stamatiadis

Vrije Universiteit Brussel

BELGIUM

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Bruce Aronow

John J Hutton MD Professor of Computational Biology and Pediatrics

Cincinnati Children’s Research Foundation

UNITED STATES

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Alfonso Martinez Arias

Professor

University of Cambridge

UNITED KINGDOM

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Christine Mummery

the novo nordisk foundation center for stem cell medicine renew leiden university medical center leiden 2333 zc the net

NETHERLANDS

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Gary Bader

Professor

University of Toronto

CANADA

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David Barry

The Francis Crick Institute

UNITED KINGDOM

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Hilde Van De Velde

Vrije Universiteit Brussel

BELGIUM

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Valdone Maciulyte

The Francis Crick Institute

UNITED KINGDOM

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Claire Simon

University of Cambridge

UNITED KINGDOM

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Georgia Kafer

Senior Lecturer

University of the Sunshine Coast

AUSTRALIA

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Greta Verheyen

Head ART laboratory

BELGIUM

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Jean‐Léon Maître

FRANCE

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Pablo Gonzalez Camara

Associate Professor of Genetics

University of Pennsylvania

UNITED STATES

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Emma Käller Lundberg

Stanford University

UNITED STATES

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Deanne Taylor

Research Associate Professor

University of Pennsylvania

UNITED STATES

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Severine Mazaud-Guittot

Université de Rennes 1

FRANCE

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Andrew Copp

Professor of Developmental Neurobiology

University College London

UNITED KINGDOM

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Thomas Bartlett

Lecturer (Assistant Professor)

University College London

UNITED KINGDOM

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Andreas Bosio

Head of Molecular Technologies and Stem Cell Therapy

GERMANY

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Alain Chédotal

FRANCE

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Karen Sermon

Vrije Universiteit Brussel

BELGIUM

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Mahesh Sangrithi

King's College London

UNITED KINGDOM

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Marius Regin

Charité - Universitätsmedizin Berlin

GERMANY

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Muzlifah Haniffa

Wellcome Sanger Institute

UNITED KINGDOM

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Claudia Gerri

Group leader

Max Planck Institute of Molecular Cell Biology and Genetics

GERMANY

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Laurent David

MCU PH

Université de Nantes

FRANCE

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Jarrett Camp

University of Basel

SWITZERLAND

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Antoine ROLLAND

Université de Rennes 1

FRANCE

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Andrew Carter

Program Leader

MRC Laboratory of Molecular Biology

UNITED KINGDOM

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Kathy Niakan

Research Interests

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Recent Grants

Articles (21)

Base editing reveals an essential role for NANOG in human embryogenesis

In-situ cryo-ET of mouse embryos reveals cytoplasmic lattices contain ubiquitin-charged E2-E3 ligase assemblies

Endogenous retrovirus control of calbindin is essential for human early embryogenesis

The vertebrate yolk sac: evolutionary origins and current advances in in vitro models

ETV4 and ETV5 orchestrate FGF-mediated lineage specification and epiblast maturation during early mouse development

ETVs dictate hPSC differentiation by tuning biophysical properties

MICA: a multi-omics method to predict gene regulatory networks in early human embryos

Transcription factor-based transdifferentiation of human embryonic to trophoblast stem cells

Smad4 is essential for epiblast scaling and morphogenesis after implantation, but nonessential before implantation

Lineage segregation in human pre-implantation embryos is specified by YAP1 and TEAD1

A conserved role of the Hippo signalling pathway in initiation of the first lineage specification event across mammals

Changing the public perception of human embryology

Human embryo models: the importance of national policy and governance review

GIANI – open-source software for automated analysis of 3D microscopy images

A roadmap for the Human Developmental Cell Atlas

TRF2-independent chromosome end protection during pluripotency

KLF17 promotes human naïve pluripotency but is not required for its establishment

The BCL-2 pathway preserves mammalian genome integrity by eliminating recombination-defective oocytes

Author Correction: Human germline genome editing

Effects of thyroid hormone on mitochondria and metabolism of human preimplantation embryos

IGF1-mediated human embryonic stem cell self-renewal recapitulates the embryonic niche

Collaborators (29)

Panagiotis Stamatiadis

Bruce Aronow

Alfonso Martinez Arias

Christine Mummery

Gary Bader

David Barry

Hilde Van De Velde

Valdone Maciulyte

Claire Simon

Georgia Kafer

Greta Verheyen

Jean‐Léon Maître

Pablo Gonzalez Camara

Emma Käller Lundberg

Deanne Taylor

Severine Mazaud-Guittot

Andrew Copp

Thomas Bartlett

Andreas Bosio

Alain Chédotal

Karen Sermon

Mahesh Sangrithi

Marius Regin

Muzlifah Haniffa

Claudia Gerri

Laurent David

Jarrett Camp

Antoine ROLLAND

Andrew Carter

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