Katja Matthias

High-quality systematic reviews (SRs) can strengthen the evidence base for prevention and health promotion. A 16-item AMSTAR 2 tool allows the appraisal of SRs by deriving a confidence rating in their results. In this cross-sectional study, we aimed to assess and compare two approaches to appraising 30 SRs of digital interventions for physical activity (PA) promotion using AMSTAR 2. Approach 1 (appraisals with 2/16 items) was used to identify SRs with critically low confidence ratings. Approach 2 (appraisals with all 16 items) was used (1) to derive the confidence ratings, (2) to identify SR strengths and weaknesses, and (3) to compare SR strengths among subgroups of SRs. The appraisal outcomes were summarized and compared using descriptive statistics. Approach 1 was quick (mean of 5 min/SR) at identifying SRs with critically low confidence ratings. Approach 2 was slower (mean of 20 min/SR), but allowed to identify SR strengths and weaknesses. Approach 2 showed that confidence ratings were low to critically low in 29/30 SRs. More strengths were identified in SRs with review protocols relative to SRs without review protocols and in newer SRs (published after AMSTAR 2 release) relative to older SRs. Only two items on AMSTAR 2 can quickly identify SRs with critical weaknesses. Although most SRs received low to critically low confidence ratings, SRs with review protocols and newer SRs tended to have more strengths. Future SRs require review protocols and better adherence to reporting guidelines to improve the confidence in their results.