Katrin Mani

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Lund University

Sweden

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Professor Katrin Mani is a faculty member at Lunds Universitet in Sweden. Her research focuses on the roles of glypicans in neural progenitor cells and their implications in cancer progression, cellular aggregation, and heparan sulfate synthesis. Notable recent articles include investigations into the modulation of pTau181 and the interactions between APP and glypican-1, which advance understanding of both neurodegenerative diseases and cancer biology.

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Expression, signaling, biomarker potential and prognostic value of glypicans in different cancers

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Articles (8)

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2025

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2024

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2023

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2023

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2022

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2022

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2021

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2020

Collaborators (3)

Derek Logan

Professor

Lund University

SWEDEN

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Theodora Tryfona

University of Cambridge

UNITED KINGDOM

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Ben Luisi

professor

University of Cambridge

UNITED KINGDOM

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Katrin Mani

Research Interests

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Recent Grants

Articles (8)

Modulation of pTau181 by Glypican‐1‐Derived Heparan Sulfate in Human Neural Progenitor Cells and ApoE4‐Expressing Induced Neurons

Dichotomous Effects of Glypican-4 on Cancer Progression and Its Crosstalk with Oncogenes

Interplay between APP and glypican-1 processing and α-synuclein aggregation in undifferentiated and differentiated human neural progenitor cells

Attenuation of cancer proliferation by suppression of glypican-1 and its pleiotropic effects in neoplastic behavior

The structure of EXTL3 helps to explain the different roles of bi-domain exostosins in heparan sulfate synthesis

Complex modulation of cytokine-induced α-synuclein aggregation by glypican-1-derived heparan sulfate in neural cells

Reversal of apolipoprotein E4-dependent or chemical-induced accumulation of APP degradation products by vitamin C-induced release of heparan sulfate from glypican-1.

Proinflammatory cytokines induce accumulation of glypican-1-derived heparan sulfate and the C-terminal fragment of β-cleaved APP in autophagosomes of dividing neuronal cells

Collaborators (3)

Derek Logan

Theodora Tryfona

Ben Luisi

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