Kazuaki Takabe

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Alfiero Foundation Chair and Professor

Roswell Park Comprehensive Cancer Center

United States

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About

Kazuaki Takabe is the Alfiero Foundation Chair and Professor at Roswell Park Cancer Institute in the United States. His research primarily focuses on breast cancer, with recent works investigating the Hippo pathway as a biomarker in HER2-positive breast cancer and examining the immune response in invasive lobular versus ductal carcinoma. Dr. Takabe's contributions also include refining breast cancer staging and exploring the potential of mesothelin in targeted therapies for triple-negative breast cancer.

Recent Grants

Grant: Close

Sphingosine-1-phosphate in breast cancer progression and lymphangiogenesis

Open Date: 2012-07-09

Close Date: 2017-04-30

Kazuaki Takabe

Research Interests

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About

Recent Grants

Articles (20)

ASO Author Reflections: Reframing Hippo Pathway Activation as a Prognostic and Predictive Biomarker in HER2-Positive Breast Cancer

Activated Hippo Pathway is Associated with a Worse Response to Trastuzumab and Worse Survival in HER2-Positive Breast Cancer

Invasive Lobular Carcinoma Has Higher Immune Response Than Invasive Ductal Carcinoma in Estrogen Receptor-Positive/Human Epidermal Growth Factor Receptor 2-Negative Breast Cancers

ASO Author Reflections: Refining Breast Cancer Staging to More Accurately Reflect Disease Biology

ASO Author Reflections: Is Mesothelin a Promising Option for Molecular Targeted Therapies in Triple Negative Breast Cancer?

ASO Visual Abstract: Mesothelin (MSLN) is Highly Expressed in Triple-Negative Breast Cancer and is Associated with Enhanced Cell Proliferation and Pro-inflammatory Tumor Microenvironment

Mesothelin (MSLN) is Highly Expressed in Triple Negative Breast Cancer and is Associated with Enhanced Cell Proliferation and Proinflammatory Tumor Microenvironment

ASO Visual Abstract: The American Joint Committee on Cancer (AJCC) Breast Cancer Staging 8th Edition is More Reflective of Cancer Biology Than the 7th Edition

The American Joint Committee on Cancer (AJCC) Breast Cancer Staging, Eighth Edition, is more Reflective of Cancer Biology than the Seventh Edition

Immune and Metabolic Reprogramming Induced by Paclitaxel, Capecitabine and Eribulin in Breast Cancer: Insights into Therapeutic Targets

E2F target score is associated with cell proliferation and survival of patients with hepatocellular carcinoma

<i>GALNT1</i> Expression Is Associated with Angiogenesis and Is a Prognostic Biomarker for Breast Cancer in Adolescents and Young Adults (AYA)

Lysophosphatidic Acid Receptor Signaling in the Human Breast Cancer Tumor Microenvironment Elicits Receptor-Dependent Effects on Tumor Progression

Decreased Lipid Phosphate Phosphatase 1/3 and Increased Lipid Phosphate Phosphatase 2 Expression in the Human Breast Cancer Tumor Microenvironment Promotes Tumor Progression and Immune System Evasion

ASO Visual Abstract: Conjugated Bile Acids Accelerate Progression of Pancreatic Cancer Metastasis via S1PR2 Signaling in Cholestasis

Conjugated Bile Acids Accelerate Progression of Pancreatic Cancer Metastasis via S1PR2 Signaling in Cholestasis

Immunotherapy: Recent Advances and Its Future as a Neoadjuvant, Adjuvant, and Primary Treatment in Colorectal Cancer

The Role of the Microbiome on the Pathogenesis and Treatment of Colorectal Cancer

Extracellular sialyltransferase st6gal1 in breast tumor cell growth and invasiveness

De-Escalating the Management of In Situ and Invasive Breast Cancer

Collaborators (4)

Fernando A. Angarita

David N. Brindley

Yoshihisa Tokumaru

Rongrong Wu

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