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Kazuki Takeda

Assistant professor

Kitasato University

Japan

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Research Interests

Pharmacology

50%

Biochemistry

20%

Toxicology

50%

Bioassay

30%

Insecticide Resistance

20%

Cytochrome P450

20%

Rodent Biology

20%

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Articles15

Development and Mechanistic Evaluation of a Lithocholic Acid Derivative as an Environmentally Safe Rodenticide

Article Link

Year:

2025

A New Class of Vitamin K Analogues Containing the Side Chain of Retinoic Acid Have Enhanced Activity for Inducing Neuronal Differentiation

Article Link

Year:

2025

Protective function of the voltage-gated potassium channel Kv11.3 in a mouse model of cardiac ischemia/reperfusion injury

Article Link

Year:

2025

Toxicity Assessment of Mixed Exposure of Nine Perfluoroalkyl Substances at Concentrations Relevant to Daily Intake

Article Link

Year:

2024

Assessment of the Aryl Hydrocarbon Receptor–Mediated Effects of Aromatic Sensitizers in Paper Recycling Effluent Employing Zebrafish Embryos and in Silico Docking

Article Link

Year:

2024

Exploring 2-methyl–substituted vitamin K3 derivatives with potent inhibitory activity against the 3CL protease of SARS-CoV-2

Article Link

Year:

2024

Sensitivity assessment of diphacinone by pharmacokinetic analysis in invasive black rats in the Bonin (Ogasawara) Archipelago, Japan.

Article Link

Year:

2024

Establishment of an evaluation method of a chemical-susceptibility for wildlife using counter-QSAR and machine learning

Article Link

Year:

2024

Development of a sandwich enzyme-linked immunosorbent assay (ELISA) to quantify γ-glutamyl-carboxylated clotting factor IX and assess redox susceptibility of anticoagulant chemicals

Article Link

Year:

2022

Observation of hapten-induced sensitization responses for the development of a mouse skin sensitization test, including the elicitation phase

Article Link

Year:

2022

Toxicokinetic analysis of the anticoagulant rodenticides warfarin & diphacinone in Egyptian fruit bats (Rousettus aegyptiacus) as a comparative sensitivity assessment for Bonin fruit bats (Pteropus pselaphon)

Article Link

Year:

2022

Sensitivity of turtles to anticoagulant rodenticides: Risk assessment for green sea turtles (Chelonia mydas) in the Ogasawara Islands and comparison of warfarin sensitivity among turtle species

Article Link

Year:

2021

The VKORC1 ER-luminal loop mutation (Leu76Pro) leads to a significant resistance to warfarin in black rats (Rattus rattus)

Article Link

Year:

2021

The effects of fipronil on emotional and cognitive behaviors in mammals

Article Link

Year:

2021

Comparison of two reducing agents dithiothreitol and tris(3-hydroxypropyl)phosphine for in vitro kinetic assay of vitamin K epoxide reductase

Article Link

Year:

2020

Collaborators13

Masanori Terasaki

Professor

Iwate University

JAPAN

Yusuke Kawai

assistant professor

Obihiro University of Agriculture and Veterinary Medicine

JAPAN

Akifumi Eguchi

Assistant professor

Chiba University

JAPAN

Tetsushi Hirano

Assistant professor

JAPAN

Masakazu Sekijima

JAPAN

Makoto SUGIYAMA

Assistant Professor

Kitasato University

JAPAN

NOBUAKI YASUO

Specially Appointed Associate Professor (Lecturer)

Tokyo Institute of Technology

JAPAN

Kosuke Otani

Assistant Professor

Kitasato University

JAPAN

Kenji Ohgane

Lecturer (PI)

Ochanomizu University

JAPAN

Hiroyuki Kagechika

Tokyo Medical and Dental University

JAPAN

Kazuyoshi Sasaoka

Specially Appointed Assistant Professor

Hokkaido University

JAPAN

Ryo Kamata

Kitasato University

JAPAN

Collins NIMAKO

PhD Student/Graduate teaching assistant

Hokkaido University

JAPAN

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Kazuki Takeda

Assistant professor

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Research Interests

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Articles15

Development and Mechanistic Evaluation of a Lithocholic Acid Derivative as an Environmentally Safe Rodenticide

A New Class of Vitamin K Analogues Containing the Side Chain of Retinoic Acid Have Enhanced Activity for Inducing Neuronal Differentiation

Protective function of the voltage-gated potassium channel Kv11.3 in a mouse model of cardiac ischemia/reperfusion injury

Toxicity Assessment of Mixed Exposure of Nine Perfluoroalkyl Substances at Concentrations Relevant to Daily Intake

Assessment of the Aryl Hydrocarbon Receptor–Mediated Effects of Aromatic Sensitizers in Paper Recycling Effluent Employing Zebrafish Embryos and in Silico Docking

Exploring 2-methyl–substituted vitamin K3 derivatives with potent inhibitory activity against the 3CL protease of SARS-CoV-2

Sensitivity assessment of diphacinone by pharmacokinetic analysis in invasive black rats in the Bonin (Ogasawara) Archipelago, Japan.

Establishment of an evaluation method of a chemical-susceptibility for wildlife using counter-QSAR and machine learning

Development of a sandwich enzyme-linked immunosorbent assay (ELISA) to quantify γ-glutamyl-carboxylated clotting factor IX and assess redox susceptibility of anticoagulant chemicals

Observation of hapten-induced sensitization responses for the development of a mouse skin sensitization test, including the elicitation phase

Toxicokinetic analysis of the anticoagulant rodenticides warfarin &amp; diphacinone in Egyptian fruit bats (Rousettus aegyptiacus) as a comparative sensitivity assessment for Bonin fruit bats (Pteropus pselaphon)

Sensitivity of turtles to anticoagulant rodenticides: Risk assessment for green sea turtles (Chelonia mydas) in the Ogasawara Islands and comparison of warfarin sensitivity among turtle species

The VKORC1 ER-luminal loop mutation (Leu76Pro) leads to a significant resistance to warfarin in black rats (Rattus rattus)

The effects of fipronil on emotional and cognitive behaviors in mammals

Comparison of two reducing agents dithiothreitol and tris(3-hydroxypropyl)phosphine for in vitro kinetic assay of vitamin K epoxide reductase

Collaborators13

Masanori Terasaki

Yusuke Kawai

Akifumi Eguchi

Tetsushi Hirano

Masakazu Sekijima

Makoto SUGIYAMA

NOBUAKI YASUO

Kosuke Otani

Kenji Ohgane

Hiroyuki Kagechika

Kazuyoshi Sasaoka

Ryo Kamata

Collins NIMAKO

How do I reach out?

Toxicokinetic analysis of the anticoagulant rodenticides warfarin & diphacinone in Egyptian fruit bats (Rousettus aegyptiacus) as a comparative sensitivity assessment for Bonin fruit bats (Pteropus pselaphon)