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Kazuma Murakami

准教授 / Associate Professor

Kyoto University

Japan

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Research Interests

Biochemistry

70%

Pharmaceutical Chemistry

10%

Amyloidosis

40%

Aptamer

30%

Antioxidant Research

20%

Protein Chemistry

20%

Metabolic Engineering

20%

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Articles12

Lysine-Targeting Inhibitors of Amyloidogenic Protein Aggregation: A Promise for Neurodegenerative Proteinopathies

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Year:

2025

Neurotoxic Implications of Human Coronaviruses in Neurodegenerative Diseases: A Perspective from Amyloid Aggregation

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Year:

2025

Detection of Dietary Chalcone and Flavonoid Metabolites in Mice Using UPLC–MS/MS and Their Modulatory Effects on Amyloid β Aggregation

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Year:

2023

Synthetic Biology-Based Discovery of Diterpenoid Pyrones from the Genome of <i>Eupenicillium shearii</i>

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Year:

2022

Interactions of amyloid coaggregates with biomolecules and its relevance to neurodegeneration

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Year:

2022

Aptamers targeting amyloidogenic proteins and their emerging role in neurodegenerative diseases

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Year:

2022

Lysine-targeting inhibition of amyloid β oligomerization by a green perilla-derived metastable chalcone in vitro and in vivo

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Year:

2022

Searching for Natural Products That Delay Nucleation Phase and Promote Elongation Phase of Amyloid β42 toward Alzheimer’s Disease Therapeutics

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Year:

2021

Synthetic and Biophysical Studies on the Toxic Conformer in Amyloid β with the E22Δ Mutation in Alzheimer Pathology

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Year:

2020

Detection of Amyloid β Oligomers with RNA Aptamers in AppNL-G-F/NL-G-F Mice: A Model of Arctic Alzheimer’s Disease

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Year:

2020

Synthetic biology based construction of biological activity-related library of fungal decalin-containing diterpenoid pyrones

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Year:

2020

An RNA aptamer with potent affinity for a toxic dimer of amyloid β42 has potential utility for histochemical studies of Alzheimer's disease

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Year:

2020

Collaborators6

Yohei Morishita

Projected Assistant Professor

Tohoku University

JAPAN

Kenji Mizuguchi

Osaka University

JAPAN

Hideto Miyoshi

Professor

Kyoto University

JAPAN

Kazuhiro Irie

Professor

Kyoto Daigaku

JAPAN

Thi Hong Van NGUYEN

Kyoto University

JAPAN

Kenjiro Ono

Kanazawa University Graduate School of Medical Sciences

JAPAN

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