Kazuya Shirato

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Chief

National Institute of Infectious Diseases

Japan

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About

Dr. Kazuya Shirato is the Chief at the National Institute of Infectious Diseases in Japan. His research primarily focuses on respiratory viruses, including their molecular evolution, replication in airway cells, and the impact of environmental factors on viral inactivation. Recent publications include studies on Respiratory Syncytial Virus, Human Parainfluenza Virus, and trends in respiratory infections during the COVID-19 pandemic.

Recent Grants

Grant: Close

Studies on construction of surveillance system, epidemiology, pathogenesis, and aggravating factors for respiratory syncytial virus infections

Open Date: 2023-04-01

Close Date: 2026-03-01

Grant: Close

Study on the virological difference between African and Middle Eastern strains of MERS-CoV

Open Date: 2020-04-01

Close Date: 2023-03-31

Grant: Close

Studies on the Middle East Respiratory Coronavirus in dromedary camels in Ethiopia

Open Date: 2017-04-01

Close Date: 2020-03-31

Grant: Close

Studies on the role of Ephrin-B2 and RARRES2 in replication of RS virus

Open Date: 2017-04-01

Close Date: 2020-03-31

Grant: Close

Studies on the effect of the virus isolation and passage for the original viral entry route

Open Date: 2014-04-01

Close Date: 2017-03-31

Articles (20)

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2023

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2023

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2022

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2022

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2022

Collaborators (5)

Kohji Moriishi

Professor

University of Yamanashi

JAPAN

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Masashi Sonoyama

Professor

Gunma University

JAPAN

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katsumi maenaka

Hokkaido University

JAPAN

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Koichi HASHIMOTO

Fukushima Medical University

JAPAN

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Mitsuaki Hosoya

JAPAN

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Kazuya Shirato

Research Interests

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About

Recent Grants

Articles (20)

Potential for prolonged replication of common acute respiratory viruses in air-liquid interface cultures of primary human airway cells

Respiratory Syncytial Virus Fusion Protein Epitope-Specific Antibodies and Neutralizing Activities Against Various Respiratory Syncytial Virus Strains

Changes in ORF4 of HCoV-229E under different culture conditions

Synergistic Inactivation of Airborne Viruses by Low‐Concentration Ozone With High Humidity and Temperature

Molecular Evolution of the Fusion (F) Genes in Human Parainfluenza Virus Type 2

A Clinical Isolate of Human Parainfluenza Virus 3 (Fukushima/O695/2019) Contains a Mutation in the Serial Guanosines in the RNA Editing Site of the P Gene and Produces an Atypical Number of Nongenomic Guanosine Insertions During RNA Editing

The respective roles of TMPRSS2 and cathepsins for SARS-CoV-2 infection in human respiratory organoids

Temporal Trends in Respiratory Infection Epidemics Among Pediatric Inpatients Throughout the Course of the COVID‐19 Pandemic From 2018 to 2023 in Fukushima Prefecture, Japan

Molecular Evolutionary Analyses of the Fusion Genes in Human Parainfluenza Virus Type 4

Comparison of mutations in human parainfluenza viruses during passage in primary human bronchial/tracheal epithelial air-liquid interface cultures and cell lines.

Amino Acid Substitutions in the Fusion Protein of Respiratory Syncytial Virus in Fukushima, Japan, During 2008–2023 and Their Effects

MARCH8 Restricts RSV Replication by Promoting Cellular Apoptosis Through Ubiquitin-Mediated Proteolysis of Viral SH Protein

Molecular Diversity of Human Respiratory Syncytial Virus before and during the COVID-19 Pandemic in Two Neighboring Japanese Cities

Molecular epidemiology of human metapneumovirus before and after COVID-19 in East Japan in 2017-2022.

Evidence of the simultaneous replications of active viruses in specimens positive for multiple respiratory viruses.

Development of a duplex real-time RT-PCR assay for the detection and identification of two subgroups of human metapneumovirus in a single tube.

Single Amino Acid Substitution in the Receptor Binding Domain of Spike Protein Is Sufficient To Convert the Neutralization Profile between Ethiopian and Middle Eastern Isolates of Middle East Respiratory Coronavirus

Hydrophobic Alpha-Helical Short Peptides in Overlapping Reading Frames of the Coronavirus Genome

Trends of mismatches in real-time RT-PCR assays developed by the National Institute of Infectious Diseases, Japan for Omicron variants of severe acute respiratory syndrome coronavirus 2

Essential role of TMPRSS2 in SARS-CoV-2 infection in murine airways.

Collaborators (5)

Kohji Moriishi

Masashi Sonoyama

katsumi maenaka

Koichi HASHIMOTO

Mitsuaki Hosoya

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