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Keith Ireton
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New ZealandResearch Interests
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Grant: Close
Molecular mechanism of spreading of microbial pathogens: studies with the bacterium Listeria monocytogenes
Open Date: 2011-01-01
Close Date: 2014-01-01
Articles (2)
Year:
2026
The bacterial pathogen Listeria monocytogenes induces its internalization (entry) into intestinal epithelial cells through interaction of its surface protein, internalin A (InlA), with the human cell-cell adhesion molecule, E-cadherin. While InlA-mediated entry requires bacterial stimulation of actin polymerization, it remains unknown whether additional host processes are manipulated to promote internalization.
Year:
2022
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