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Kenjirou Higashi

Chiba University

Japan

Research Interests

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Professors in Japan Professors in Pharmaceutical Chemistry Pharmaceutical Chemistry professors in Japan

Articles (31)

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Collaborators (6)

Etsuo Yonemochi

Dean, Professor

International University of Health and Welfare

JAPAN

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Takefumi Yamashita

Associate Professor

University of Tokyo

JAPAN

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Koji Okuwaki

Assistant Professor

Ritsumeikan University

JAPAN

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Mayumi Ikeda-Imafuku

Assistant professor

Wakayama Medical University

JAPAN

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Toshiro Fukami

Meiji Pharmaceutical University

JAPAN

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Nimmy Kumari

Assistant Professor

Birla Institute of Technology Mesra

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Kenjirou Higashi

Research Interests

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Articles (31)

Elucidating the role of TPGS in felodipine/PVPVA amorphous solid dispersions during water uptake: dissipative particle dynamics simulations using quantum chemistry-based interaction parameters

In Situ X-ray Scattering for Doxorubicin-Loaded Liposomes to Elucidate the Morphological Change Mechanism Depending on the Cooling Rate and Cholesterol Content

Correlation of Molecular State and Drug Release in Irinotecan-Loaded Liposomes Using Different Trapping Agents

Development of Small Interfering RNA-Loaded Extracellular Vesicles via a High-Pressure Homogenization Approach

Visualizing the Spatiotemporal Redistribution of Drugs in Destabilizing Nanoemulsions: A Quantitative Solution 1H NMR Approach

Thermo and Bile Dual-Responsive Nanocarrier Composed of Cholesteryl Oleate Crystal Core and Nanosheet Shell of γ-cyclodextrin Inclusion Complex Crystal

<i>In situ</i> SAXS and rheological correlation of microstructural evolution during the sol-gel transition of Poloxamer 407 modulated by Poloxamer 188

Clarifying pair interaction potential between poloxamer 407 micelles solvated into phosphate-buffered saline in sol-gel-sol transition

Continuous droplet freezing enables stable powder formulation of extracellular vesicles for therapeutic applications

Role of carriers and pre-dissolved polymers in drug-rich nanodroplet formation during dissolution of amorphous drug formulations

Scalable Preparation of Extracellular Vesicles Encapsulating Anticancer Drugs by High-Pressure Homogenization for Targeted Cancer Therapy

Thermodynamic Perspectives on the Impact of a Second Drug on Amorphous Drug Solubility

Structural Analysis of Anhydrate Salt Cocrystal of Ibuprofen and Loxoprofen Sodium with Fructose by Single-Crystal X-ray Diffraction and Solid-State NMR

Elucidating the Mechanistic Shortcomings of Acetazolamide Cocrystals in Harnessing the Anticipated Solubility and Permeability Advantages

Mechanistic insights into drug supersaturation during lipid digestion in self-emulsifying drug delivery systems: A cryo-TEM and NMR study

Impact of Microemulsion Oil Components on Liquid–Liquid Phase Separation of a Supersaturated Drug Revealed by Cryo-TEM and 1H NMR Analysis

A Post-Encapsulation Method for the Preparation of mRNA-LNPs via the Nucleic Acid-Bridged Fusion of mRNA-Free LNPs

Cholesterol depletion suppresses thermal necrosis resistance by alleviating an increase in membrane fluidity

Impact of colloidal drug-rich droplet size and amorphous solubility on drug membrane permeability: A comprehensive analysis

Nanomorphology tuning in doxorubicin-loaded liposomes via cooling-induced doxorubicin-crystallization and membrane phase transition

Designing a Novel Coamorphous Salt Formulation of Telmisartan with Amlodipine to Enhance Permeability and Oral Absorption

Vapor-Phase-Mediated Encapsulation of Guest Drug Molecules in the Hexagonal Columnar Form Structure of Polyethylene Glycol/γ-Cyclodextrin-Polypseudorotaxane

Quantitative Analysis of Drug Supersaturation Region by Temperature-Variable Nuclear Magnetic Resonance Measurements, Part 1: Effects of Polymer and Drug Chiralities

Quantitative Analysis of Drug Supersaturation Region by Temperature-Variable Nuclear Magnetic Resonance Measurements, Part 2: Effects of Solubilizer

Supersaturation maintenance of carvedilol and chlorthalidone by cyclodextrin derivatives: Pronounced crystallization inhibition ability of methylated cyclodextrin

Understanding the rod-to-tube transformation of self-assembled ascorbyl dipalmitate lipid nanoparticles stabilized with PEGylated lipids

A study combining magic-angle spinning NMR and small-angle X-ray scattering on the interaction in the mixture of poly(benzyl methacrylate) and ionic liquid 1-ethyl-3-methylimidazolium bis(trifluoromethanesulfonyl)amide

Unusual Correlation between the Apparent Amorphous Solubility of a Drug and Solubilizer Concentration Revealed by NMR Analysis

Drug-Loaded Nanocarriers Composed of Cholesteryl Oleate Crystal Cores and Multiple-Nanosheet Shells of γ-Cyclodextrin Inclusion Complex Crystals

Multistep Crystallization of Pharmaceutical Amorphous Nanoparticles via a Cognate Pathway of Oriented Attachment: Direct Evidence of Nonclassical Crystallization for Organic Molecules

Preparation of redispersible dry nanoemulsion using chitosan-octenyl succinic anhydride starch polyelectrolyte complex as stabilizer

Collaborators (6)

Etsuo Yonemochi

Takefumi Yamashita

Koji Okuwaki

Mayumi Ikeda-Imafuku

Toshiro Fukami

Nimmy Kumari

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