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Kenneth King Yip Cheng

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Assistant Professor

The Hong Kong Polytechnic University

Hong Kong

Research Interests

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Professors in Biochemistry

Recent Grants

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The Oncogene MDM2 as A New Mediator of Obesity-Induced Nonalcoholic Fatty Liver Disease

Open Date: 2018-04-01

Close Date: 2020-03-01

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The E3 Ubiquitin Ligase MDM2 Regulates Adipose Tissue Macrophage Inflammation via Metabolic Reprogramming in Obesity

Open Date: 2018-01-01

Close Date:

Grant: Close

Adipocyte MDM2 as Adipocyte MDM2 as a key determinant of metabolic homeostasis

Open Date: 2017-01-01

Close Date: 2019-01-01

Grant: Close

The novel role of hematopoietic APPL1 in regulating adipose tissue inflammation and insulin resistance in obesity

Open Date: 2016-01-01

Close Date: 2018-01-01

Grant: Close

The MDM2-p53 pathway as a novel regulator of glucose-stimulated insulin secretion in pancreatic beta cells

Open Date: 2015-01-01

Close Date: 2017-01-01

Articles (20)

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2023

Collaborators (6)

Aimin Xu

Chair Professor

The University of Hong Kong

HONG KONG

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Jordy Evan Sulaiman

Research Assistant Professor

The Hong Kong Polytechnic University

HONG KONG

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Georg Kranz

Assoc. Prof

The Hong Kong Polytechnic University

HONG KONG

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Hannah Xiaoyan Hui

The Chinese University of Hong Kong (CUHK)

HONG KONG

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Zhe Huang

Associate Professor

Shanghai Jiao Tong University

CHINA

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Martin Wabitsch

Head of Divison of Paediatric Endocrinology and Diabetes

University Hospital Ulm

GERMANY

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Kenneth King Yip Cheng

Research Interests

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Recent Grants

Articles (20)

MDM2 deletion and its associated p53 activation in subcutaneous white adipose tissue induce hepatic fibrosis via galectin-3 in a mouse model

Oral pathogens meet the gut microbiome: new mechanistic insights on systemic disease

Subcutaneous white adipose tissue–derived extracellular vesicles maintain intestinal homeostasis via IgA biosynthesis in aging mice

Branched-chain α-keto acids impair glucose-stimulated insulin secretion in pancreatic β-cells under diabetes by reactivating the LDHA-lactate axis

β-cell FMO3-produced TMAO prevents NF-κB-mediated senescence and inflammation in ageing and diabetic conditions

Causal role of genetically predicted impairment of branched‐chain amino acid catabolism on insulin secretion and insulin resistance in type 2 diabetes

Application of age- and sex-specific reference intervals for thyroid-stimulating hormone and free thyroxine in evaluating incidence and trends of thyroid dysfunctions: A population-based cohort study

How muscle talks to brain: apelin protein mediates exercise-induced antidepressant effects

Rapid antidepressant effect of single-bout exercise is mediated by adiponectin-induced APPL1 nucleus translocation in anterior cingulate cortex

Proteomic study of <i>Akkermansia muciniphila</i> and <i>Bifidobacterium</i> species co-culture under different carbon sources

Adipocyte FMO3-derived TMAO induces WAT dysfunction and metabolic disorders by promoting inflammasome activation in ageing

Branched‐chain amino acid metabolism: Pathophysiological mechanism and therapeutic intervention in metabolic diseases

Gene therapy prevents onset of mitochondrial cardiomyopathy in neonatal mice with Ndufs6 deficiency

Gut microbiome-adipose crosstalk modulates soluble IL-6 receptor influencing exercise responsiveness in glycemic control and insulin sensitivity

Taurine Alleviates Pancreatic β-Cell Senescence by Inhibition of p53 Pathway

MDM2 induces pro-inflammatory and glycolytic responses in M1 macrophages by integrating iNOS-nitric oxide and HIF-1α pathways in mice

The mitochondrial enzyme pyruvate carboxylase restricts pancreatic β-cell senescence by blocking p53 activation

From exosomes to mitochondria and myocardial infarction: Molecular insight and therapeutic challenge

Polygoni Cuspidati Rhizoma et Radix extract activates TFEB and alleviates hepatic steatosis by promoting autophagy

Editorial: Metabolic associated fatty liver disease: clinical perspectives from pathogenesis to diagnosis and treatment

Collaborators (6)

Aimin Xu

Jordy Evan Sulaiman

Georg Kranz

Hannah Xiaoyan Hui

Zhe Huang

Martin Wabitsch

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