Kenzo Yamatsugu

Professor

Chiba University

Japan

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About

Kenzo Yamatsugu is a Professor at Chiba University in Japan. His research focuses on innovative approaches in chemical biology, including the development of antibody-mimetic drug conjugates and catalytic transformations in carbohydrate chemistry. Recent publications highlight his work on Umpolung Phosphorylation of Tyrosine and designer adaptor proteins for peptide conversion. Professor Yamatsugu's contributions advance the field of targeted therapies and in-cell protein modifications.

Articles (18)

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2024

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2024

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2024

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2023

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2023

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2023

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2023

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2023

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2022

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2022

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2022

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2021

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2021

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2021

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2021

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2020

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2020

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2020

Collaborators (7)

Harunobu Mitsunuma

Assistant professor

University of Tokyo

JAPAN

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Motomu Kanai

JAPAN

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Yuko Sato

Research Assistant Professor

Tokyo Institute of Technology

JAPAN

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Takefumi Yamashita

University of Tokyo

JAPAN

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Hiroto Katoh

JAPAN

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Akira Sugiyama

Asisstant professor

University of Tokyo

JAPAN

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Shigehiro Kawashima

The Univeristy of Tokyo

JAPAN

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Kenzo Yamatsugu

Research Interests

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About

Articles (18)

Antibody-mimetic drug conjugate with efficient internalization activity using anti-HER2 VHH and duocarmycin

Umpolung Phosphorylation of Tyrosine via 1,2-Phospha-Brook Rearrangement

Antibody-mimetic drug conjugate with efficient internalization activity using anti-HER2 VHH and duocarmycin

Catalytic Approaches to Chemo- and Site-Selective Transformation of Carbohydrates

A chemical catalyst enabling histone acylation with endogenous acyl-CoA

Designer Adaptor Proteins for Functional Conversion of Peptides to Small-Molecule Ligands toward In-Cell Catalytic Protein Modification

Designer Adaptor Proteins for Functional Conversion of Peptides to Small-Molecule Ligands toward In-Cell Catalytic Protein Modification

Catalytic Approaches to Chemo- and Site-Selective Transformation of Carbohydrates

Pathological complete remission of relapsed tumor by <scp>photo‐activating</scp> antibody–mimetic drug conjugate treatment

Antibody mimetic drug conjugate manufactured by high-yield Escherichia coli expression and non-covalent binding system

Pathological complete remission of relapsed tumor by photo-activating antibody-mimetic drug conjugate treatment

Live-cell epigenome manipulation by synthetic histone acetylation catalyst system

Axially-substituted silicon phthalocyanine payloads for antibody-drug conjugates

Live-Cell Protein Modification by Boronate-Assisted Hydroxamic Acid Catalysis

A Single-Step Asymmetric Phosphodiester Synthesis from Alcohols with Phosphoenolpyruvate Phosphodiester

Sulfanylmethyldimethylaminopyridine as a Useful Thiol Additive for Ligation Chemistry in Peptide/Protein Synthesis

Catalytic Chemoselective O-Phosphorylation of Alcohols

Synthetic hyperacetylation of nucleosomal histones

Collaborators (7)

Harunobu Mitsunuma

Motomu Kanai

Yuko Sato

Takefumi Yamashita

Hiroto Katoh

Akira Sugiyama

Shigehiro Kawashima

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