Kerstin Lagerstrand

The University of Gothenburg’s Sahlgrenska Academy is offering several fully funded PhD positions in Medical Science at the Institute of Clinical Sciences. These positions are based in the Departments of Biomaterials, Oncology, and Medical Radiation Sciences, and focus on cutting-edge research in biomaterials, post-radiation intestinal health, and advanced MRI/data-driven approaches for low back pain diagnosis. Project 1: Mechanical overload impact on the immunocompromized peri-implant zone and osseointegration in osteoporotic bone This project investigates the cellular and molecular mechanisms at the bone-implant interface, particularly in osteoporotic conditions and under mechanical overload. The research aims to understand how engineered surface topographies can steer bone response toward stable osseointegration. The work involves advanced cellular, molecular, and imaging techniques, in vitro and in vivo models, and international collaboration with McMaster University, Canada. More info . Project 2: Inflammation as a Treatment Target in Chronic Radiation-Induced Bowel Dysfunction This project addresses the chronic intestinal dysfunctions that arise after pelvic radiotherapy, focusing on low-grade inflammation and its contribution to symptoms. The research combines laboratory work (omics analyses, basic techniques) with clinical pilot studies, including protocol development, sample collection, and analysis. Proficiency in Swedish is required due to patient-oriented research. More info . Project 3: From imaging to insight: Loading-based MRI and data-driven approaches for low back pain diagnosis This project aims to develop and evaluate MRI methods and data-driven image analysis to identify biomarkers for nonspecific low back pain. The research involves advanced MRI, image registration, texture analysis, and predictive modeling, with a focus on integrating imaging biomarkers and clinical data. Experience with MR images and programming (Matlab, Python) is advantageous. More info . Eligibility & Requirements: Applicants must have a second-cycle degree or equivalent, with strong backgrounds in relevant fields such as biomaterials, cell/molecular biology, imaging, or clinical research. English proficiency is required; Swedish proficiency is needed for some projects. Additional merits include experience in cell culture, imaging, animal models, MR image processing, and programming. Personal suitability and the ability to work independently and collaboratively are important. Funding: All positions are fully funded as doctoral employment at the University of Gothenburg, with salaries set individually. The positions are full-time for four years, with possible departmental duties up to 20%. Application: Apply via the University of Gothenburg’s recruitment portal by 2026-02-23. Submit a personal letter, CV, diploma and transcripts, and proof of English proficiency. For more information, contact the listed supervisors or visit the provided links. For international applicants, resources about moving to Gothenburg and university services are available. The university values diversity and equal opportunity in its working environment.