kevin lynch

Professor

University of Virginia

United States

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Articles (7)

Year:

2023

Year:

2022

Year:

2022

Year:

2022

Year:

2021

Year:

2020

Year:

2020

Collaborators (5)

Shinji Tanaka

University of Tokyo

JAPAN

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Vlad Serbulea

Research Assistant Professor

University of Virginia

UNITED STATES

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Anne M. Brown

Assistant Professor - Science Informatics Consultant & Health Analytics Coordinator

Virginia Tech

UNITED STATES

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David Bevan

Professor

Virginia Tech

UNITED STATES

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Webster Santos

Professor

Virginia Polytechnic Institute and State University

UNITED STATES

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kevin lynch

Research Interests

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Articles (7)

2-Aminobenzoxazole Derivatives as Potent Inhibitors of the Sphingosine-1-Phosphate Transporter Spinster Homolog 2 (Spns2)

Sphingosine 1-phosphate signaling in perivascular cells enhances inflammation and fibrosis in the kidney.

Sphingosine Kinase 2 Inhibitors: Rigid Aliphatic Tail Derivatives Deliver Potent and Selective Analogues

Discovery of In Vivo Active Sphingosine-1-phosphate Transporter (Spns2) Inhibitors

Probing the substitution pattern of indole-based scaffold reveals potent and selective sphingosine kinase 2 inhibitors

Mechanism of sphingosine 1-phosphate clearance from blood.

Discovery of a Small Side Cavity in Sphingosine Kinase 2 that Enhances Inhibitor Potency and Selectivity

Collaborators (5)

Shinji Tanaka

Vlad Serbulea

Anne M. Brown

David Bevan

Webster Santos

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