Kevin McHugh

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Assistant Professor

United States

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About

Dr. Kevin McHugh is an Assistant Professor at William Marsh Rice University in the United States. His research focuses on biodegradable polymers, drug delivery systems, and immunology, as evidenced by his recent publications on photocurable poly(glycerol sebacate), peptide hydrogels, and vaccine adjuvants. He is also exploring innovative strategies for enhancing drug release kinetics and antigen activation through nanofibrous structures.

Recent Grants

Grant: Close

Personalized Immunotherapy for Atypical Pulmonary Carcinoids

Open Date: 2023-01-01

Close Date: 2024-01-01

Grant: Close

Personalized Mutation-Targeted Immunotherapy for Glioblastoma Multiforme

Open Date: 2022-10-01

Close Date: 2026-09-01

Grant: Close

Targeted delivery of microbiome-modulating metabolites to the lower intestine to reduce systemic toxicities of cancer therapy

Open Date: 2022-09-01

Close Date: 2024-08-01

Grant: Close

The Cancer Genome as a Novel Target for Malignant Osteosarcoma Immunotherapy

Open Date: 2022-06-01

Close Date: 2023-05-31

Grant: Close

Mutation-Targeted Immunotherapy for the Treatment of Rare Cancers

Open Date: 2021-09-30

Close Date: 2022-09-29

Articles (18)

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2020

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2020

Collaborators (6)

Francisco Altamirano

Assistant Professor

Houston Methodist Research Institute

UNITED STATES

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Laura Segatori

Associate Professor

Rice University

UNITED STATES

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Tsvetelina Baryakova

Rice University

UNITED STATES

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Antara Pal

Lecturer

Malmö University

SWEDEN

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Jeffrey Hartgerink

Professor

Rice University

UNITED STATES

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Aaron R. Wheeler

University of Toronto

CANADA

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Kevin McHugh

Research Interests

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About

Recent Grants

Articles (18)

A TLR7 Agonist Conjugated to a Nanofibrous Peptide Hydrogel as a Potent Vaccine Adjuvant

Novel Approaches to Label the Surface of S. aureus with DBCO for Click Chemistry-Mediated Deposition of Sensitive Cargo

Methacrylated poly(glycerol sebacate) as a photocurable, biocompatible, and biodegradable polymer with tunable degradation and drug release kinetics

Nanofibrous Peptide Hydrogels Leveraging Histidine to Modulate pH-Responsive Supramolecular Assembly and Antibody Release

Histone demethylase KDM5 regulates cardiomyocyte maturation by promoting fatty acid oxidation, oxidative phosphorylation, and myofibrillar organization

Intra‐lymph node crosslinking of antigen‐bearing polymers enhances humoral immunity and dendritic cell activation

Probing the Effects of Chirality on Self-Assembling Peptides: Hydrogel Formation, Degradation, Antigen Release, and Adjuvancy

Aqueous Grown Quantum Dots with Robust Near-Infrared Fluorescence for Integrated Traumatic Brain Injury Diagnosis and Surgical Monitoring

Strategies for overcoming protein and peptide instability in biodegradable drug delivery systems

A Scalable Platform for Fabricating Biodegradable Microparticles with Pulsatile Drug Release

Overcoming barriers to patient adherence: the case for developing innovative drug delivery systems

Dynamic Imine Bonding Facilitates Mannan Release from a Nanofibrous Peptide Hydrogel

Translating diagnostics and drug delivery technologies to low-resource settings

Bright, Magnetic NIR-II Quantum Dot Probe for Sensitive Dual-Modality Imaging and Intensive Combination Therapy of Cancer

Novel Vaccine Adjuvants as Key Tools for Improving Pandemic Preparedness

Employing Drug Delivery Strategies to Overcome Challenges Using TLR7/8 Agonists for Cancer Immunotherapy

Zero-order drug delivery: State of the art and future prospects

Engineered PLGA microparticles for long-term, pulsatile release of STING agonist for cancer immunotherapy

Collaborators (6)

Francisco Altamirano

Laura Segatori

Tsvetelina Baryakova

Antara Pal

Jeffrey Hartgerink

Aaron R. Wheeler

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